(Q35795478)

English

Click modification in the N6 region of A3 adenosine receptor-selective carbocyclic nucleosides for dendrimeric tethering that preserves pharmacophore recognition.

scientific article published on 11 January 2012

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175234%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Click modification in the N6 region of A3 adenosine receptor-selective carbocyclic nucleosides for dendrimeric tethering that preserves pharmacophore recognition (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175234%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kenneth A. Jacobson

7

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18 January 2020

6

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Zhan-Guo Gao

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18 January 2020

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Dilip K Tosh

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18 January 2020

Francesca Deflorian

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Francesca Deflorian

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18 January 2020

5

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Lena S Yoo

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18 January 2020

author name string

Khai Phan

2

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18 January 2020

Qiang Wei

4

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18 January 2020

publication date

11 January 2012

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18 January 2020

Bioconjugate Chemistry

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18 January 2020

23

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18 January 2020

2

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18 January 2020

232-247

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18 January 2020

Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics

1 reference

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Asymmetry of GPCR oligomers supports their functional relevance.

1 reference

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

1 reference

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Adenosine receptors in health and disease

1 reference

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1 reference

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Dendrimer-based MRI contrast agents: the effects of PEGylation on relaxivity and pharmacokinetics

1 reference

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Structure of an agonist-bound human A2A adenosine receptor

1 reference

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International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update

1 reference

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GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

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Luminescence targeting and imaging using a nanoscale generation 3 dendrimer in an in vivo colorectal metastatic rat model.

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Design, synthesis, and binding of homologated truncated 4'-thioadenosine derivatives at the human A3 adenosine receptors

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The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions

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Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3.

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Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide

1 reference

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Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

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Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

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27 July 2018

2-Dialkynyl derivatives of (N)-methanocarba nucleosides: 'Clickable' A(3) adenosine receptor-selective agonists

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Synthesis and pharmacological characterization of [(125)I]MRS5127, a high affinity, selective agonist radioligand for the A3 adenosine receptor

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Applications of orthogonal "click" chemistries in the synthesis of functional soft materials

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Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species.

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Synthesis and applications of biomedical and pharmaceutical polymers via click chemistry methodologies.

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Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.

1 reference

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Click chemistry and bioorthogonal reactions: unprecedented selectivity in the labeling of biological molecules.

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Molecular modeling of a PAMAM-CGS21680 dendrimer bound to an A2A adenosine receptor homodimer.

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Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trial

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An efficient, inexpensive, and shelf-stable diazotransfer reagent: imidazole-1-sulfonyl azide hydrochloride

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Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists

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(N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists.

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N6-substituted D-4'-thioadenosine-5'-methyluronamides: potent and selective agonists at the human A3 adenosine receptor

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1,2,4-Triazolo[5,1-i]purine derivatives as highly potent and selective human adenosine A(3) receptor ligands

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125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BC200526C

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22175234%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

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18 January 2020

PubMed publication ID

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Europe PubMed Central

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18 January 2020

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