(Q35796032)

English

Topographic abnormalities of proinsulin to insulin conversion in functioning human insulinomas. Comparison of immunoelectron microscopic and clinical data

scientific article published on August 1, 1995

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

Topographic abnormalities of proinsulin to insulin conversion in functioning human insulinomas. Comparison of immunoelectron microscopic and clinical data (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

author name string

J. Roth

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

P. Komminoth

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

P. U. Heitz

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

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1 August 1995

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7639339/pdf/?tool=EBI

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7639339/?tool=EBI

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

http://ajp.amjpathol.org/cgi/content/abstract/147/2/489

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

https://europepmc.org/articles/PMC1869814

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

https://europepmc.org/articles/PMC1869814?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7639339

4 July 2024

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

147

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

489-502

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

Slow cleavage at the proinsulin B-chain/connecting peptide junction associated with low levels of endoprotease PC1/3 in transformed beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Nonconverted, amino acid analog-modified proinsulin stays in a Golgi-derived clathrin-coated membrane compartment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Direct identification of prohormone conversion site in insulin-secreting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Recognition of human insulin and proinsulin by monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Constitutive and regulated secretion of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Use of a synthetic peptide antigen to generate antisera reactive with a proteolytic processing site in native human proinsulin: demonstration of cleavage within clathrin-coated (pro)secretory vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

An antibody specific for an endoproteolytic cleavage site provides evidence that pro-opiomelanocortin is packaged into secretory granules in AtT20 cells before its cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

The insulin secretory granule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Biogenesis of secretory granules. Implications arising from the immature secretory granule in the regulated pathway of secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Protein discharge from immature secretory granules displays both regulated and constitutive characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Characterization of the immature secretory granule, an intermediate in granule biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Contrasting of Lowicryl K4M thin sections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

The new enzymology of precursor processing endoproteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Familial hyperproinsulinemia. An autosomal dominant defect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Ultrastructural localization of intracellular antigens by the use of protein A-gold complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

The use of avidin-biotin interaction in immunoenzymatic techniques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

11 July 2018

Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs. Lack of effect on rate of release of modified products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

25 September 2018

Familial hyperproinsulinemia due to a proposed defect in conversion of proinsulin to insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

25 September 2018

Functional and Morphologic Characterization of Human Insulinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1869814

25 September 2018

Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreatic tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Production and Characterization of Monoclonal Antibodies Specific for Human Proinsulin Using a Sensitive Microdot Assay Procedure*

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Proinsulin-Specific Antigenic Determinants Identified by Monoclonal Antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Applications of immunocolloids in light microscopy. III. Demonstration of antigenic and lectin-binding sites in semithin resin sections

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of exogenous hyperinsulinemia on proinsulin secretion in normal man, obese subjects, and patients with insulinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic endocrine tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of proinsulin and insulin in human insulinoma: preliminary immunohistochemical results

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of non-specific interactions of gold-labeled reagents on tissue sections

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postembedding labeling on Lowicryl K4M tissue sections: detection and modification of cellular components

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of pro-ACTH/endorphin begins in the Golgi complex of pituitary corticotropes and AtT-20 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trimeric G-proteins of the trans -Golgi network are involved in the formation of constitutive secretory vesicles and immature secretory granules

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Versatility of anti-horseradish peroxidase antibody-gold complexes for cytochemistry and in situ hybridization: preparation and application of soluble complexes with streptavidin-peroxidase conjugates and biotinylated antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution patterns of proinsulin and insulin in human insulinomas: an immunohistochemical analysis in 76 tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and morphological investigations of 30 human insulinomas. Correlation between the tumour content of insulin and proinsulin-like components and the histological and ultrastructural appearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/7639339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7639339%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

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