(Q35802247)

English

A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling.

scientific article published on 30 December 2011

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210881%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210881%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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19 January 2020

Timothy J. Stalker

9

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19 January 2020

Debra K. Newman

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object named as

Debra K Newman

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19 January 2020

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Peisong Ma

1

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19 January 2020

Aleksandra Cierniewska

2

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19 January 2020

Rachel Signarvic

3

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19 January 2020

Marcin Cieslak

4

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19 January 2020

Hong Kong

5

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19 January 2020

Andrew J Sinnamon

6

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19 January 2020

Lawrence F Brass

10

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19 January 2020

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30 December 2011

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19 January 2020

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19 January 2020

119

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19 January 2020

8

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19 January 2020

1935-1945

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19 January 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3293648/fullTextXML

based on heuristic

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Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

R4 RGS proteins: regulation of G-protein signaling and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

How regulators of G protein signaling achieve selective regulation

1 reference

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11 July 2018

Activation of platelet function through G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Spinophilin: from partners to functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Discovery of a novel shp2 protein tyrosine phosphatase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Molecular and biochemical evidence for the presence of type III adenylyl cyclase in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Identification of RGS2 and type V adenylyl cyclase interaction sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Cloning and characterization of a novel regulator of G protein signalling in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Impaired conditioned taste aversion learning in spinophilin knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

RGS18 is a myeloerythroid lineage-specific regulator of G-protein-signalling molecule highly expressed in megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III.

1 reference

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11 July 2018

Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Immune inhibitory receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Spinophilin regulates the formation and function of dendritic spines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

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11 July 2018

RGS10 is a selective activator of G alpha i GTPase activity

1 reference

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11 July 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

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11 July 2018

Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits

1 reference

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11 July 2018

Prostaglandins and platelets

1 reference

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11 July 2018

Isolation of a src homology 2-containing tyrosine phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293648

11 July 2018

The expression patterns of RGS transcripts in platelets.

1 reference

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25 September 2018

Divergent roles of SHP-2 in ERK activation by leptin receptors

1 reference

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25 September 2018

Protein tyrosine phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22210881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine phosphatase SHP-1 fails to associate with cytoskeleton but is normally phosphorylated upon thrombin stimulation of thrombasthenic platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22210881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of a Role for SHP-1 in Platelet Activation by the Collagen Receptor Glycoprotein VI

1 reference

https://pubmed.ncbi.nlm.nih.gov/22210881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2011-10-387910

1 reference

Europe PubMed Central

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19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210881%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22210881%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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