(Q35807430)

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Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species

scientific article published on 13 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

reactive oxygen species

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inferred from title

Jun Ninomiya-Tsuji

5

object named as

Jun Ninomiya-Tsuji

1 reference

Europe PubMed Central

10 August 2017

PMC publication ID

Kunihiro Matsumoto

4

object named as

Kunihiro Matsumoto

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

Emily Omori

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Maiko Inagaki

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Yuji Mishina

3

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Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

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publication date

13 February 2012

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PMC publication ID

10 August 2017

109

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

3365-3370

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Genetics and pathogenesis of inflammatory bowel disease

1 reference

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11 July 2018

NF-κB in immunobiology.

1 reference

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11 July 2018

TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium

1 reference

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11 July 2018

Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process

1 reference

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11 July 2018

Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

Direct activation of protein kinases by unanchored polyubiquitin chains

1 reference

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Ageing, oxidative stress and cancer: paradigms in parallax

1 reference

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11 July 2018

TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling

1 reference

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11 July 2018

Generation of a conditional mutant allele for Tab1 in mouse

1 reference

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Molecular mechanisms of Nrf2-mediated antioxidant response

1 reference

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11 July 2018

TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

1 reference

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11 July 2018

Protein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cells

1 reference

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11 July 2018

Signaling to NF-kappaB by Toll-like receptors

1 reference

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11 July 2018

Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway

1 reference

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11 July 2018

Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

1 reference

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11 July 2018

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

1 reference

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11 July 2018

Ubiquitin, TAK1 and IKK: is there a connection?

1 reference

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11 July 2018

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress

1 reference

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11 July 2018

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

Nrf2 signaling in coordinated activation of antioxidant gene expression

1 reference

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11 July 2018

Identification of a human NF-kappaB-activating protein, TAB3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

TAB3, a new binding partner of the protein kinase TAK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

1 reference

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Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)

1 reference

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11 July 2018

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

1 reference

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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295251

11 July 2018

An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK

1 reference

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

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Regulation of the TAK1 signaling pathway by protein phosphatase 2C

1 reference

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Oxidants, oxidative stress and the biology of ageing

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TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

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TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

1 reference

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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

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Essential function for the kinase TAK1 in innate and adaptive immune responses

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TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway

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Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.

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Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein

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Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

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21 January 2018

Identifiers

10.1073/PNAS.1116188109

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

2012PNAS..109.3365O

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

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