(Q35816903)

26490873

10 August 2017

title

Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression (English)

1 reference

10 August 2017

1 reference

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605427&resulttype=core&format=json

15 May 2020

Anders Björklund

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605427&resulttype=core&format=json

15 May 2020

author name string

Nikolaos Volakakis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605427&resulttype=core&format=json

15 May 2020

Katarina Tiklova

2

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15 May 2020

Mickael Decressac

3

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15 May 2020

Maria Papathanou

4

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15 May 2020

Bengt Mattsson

5

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15 May 2020

Linda Gillberg

6

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15 May 2020

Thomas Perlmann

9

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15 May 2020

language of work or name

English

0 references

publication date

1 October 2015

1 reference

26490873

10 August 2017

published in

Journal of Neuroscience

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15 May 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605427&resulttype=core&format=json

15 May 2020

issue

42

1 reference

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15 May 2020

page(s)

14370-14385

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describes a project that uses

15 May 2020

ImageQuant

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11 June 2022

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ImageJ

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11 June 2022

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cites work

Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: multinational phase II-III trial results

1 reference

12 December 2020

Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells.

1 reference

12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

12 December 2020

1 reference

12 December 2020

Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

1 reference

12 December 2020

Nuclear localization of alpha-synuclein and its interaction with histones

1 reference

12 December 2020

Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons

1 reference

12 December 2020

Analysis of alpha-synuclein-associated proteins by quantitative proteomics

1 reference

12 December 2020

Subcellular localisation of recombinant alpha- and gamma-synuclein.

1 reference

12 December 2020

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

1 reference

12 December 2020

Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization

1 reference

12 December 2020

Linker histone H1 binds to disease associated amyloid-like fibrils

1 reference

12 December 2020

Identification of novel proteins associated with both alpha-synuclein and DJ-1

1 reference

12 December 2020

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

1 reference

12 December 2020

Impairment of microtubule-dependent trafficking by overexpression of alpha-synuclein

1 reference

12 December 2020

How to make a mesodiencephalic dopaminergic neuron

1 reference

12 December 2020

Analysis of alpha-synuclein, dopamine and parkin pathways in neuropathologically confirmed parkinsonian nigra.

1 reference

12 December 2020

Brain neutral lipids mass is increased in alpha-synuclein gene-ablated mice

1 reference

12 December 2020

Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody

1 reference

12 December 2020

DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.

1 reference

12 December 2020

Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease

1 reference

12 December 2020

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

12 December 2020

A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P + A53T transgenic mice.

1 reference

12 December 2020

1 reference

12 December 2020

Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.

1 reference

12 December 2020

Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals.

1 reference

12 December 2020

PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction

1 reference

12 December 2020

Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression

1 reference

12 December 2020

Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons

1 reference

12 December 2020

Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain

1 reference

12 December 2020

Differential expression analysis for sequence count data

1 reference

12 December 2020

α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity

1 reference

12 December 2020

Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease

1 reference

12 December 2020

Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa

1 reference

12 December 2020

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

1 reference

12 December 2020

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease

1 reference

12 December 2020

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

1 reference

12 December 2020

Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1

1 reference

12 December 2020

Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease

1 reference

12 December 2020

α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons

1 reference

12 December 2020

Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein

1 reference

12 December 2020

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

1 reference

12 December 2020

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

1 reference

12 December 2020

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

1 reference

12 December 2020

9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons

1 reference

12 December 2020

Synaptic dysfunction in synucleinopathies.

1 reference

12 December 2020

Smart-seq2 for sensitive full-length transcriptome profiling in single cells.

1 reference

12 December 2020

Low dose bexarotene treatment rescues dopamine neurons and restores behavioral function in models of Parkinson's disease

1 reference

12 December 2020

NURR1 in Parkinson disease--from pathogenesis to therapeutic potential

1 reference

12 December 2020

PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1.

1 reference

12 December 2020

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

1 reference

12 December 2020

Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity

1 reference

12 December 2020

RXRs: collegial partners

1 reference

12 December 2020

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

1 reference

12 December 2020

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

1 reference

12 December 2020

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.

1 reference

12 December 2020

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

12 December 2020

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1

1 reference

12 December 2020

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

1 reference

12 December 2020

Dopamine neuron agenesis in Nurr1-deficient mice

1 reference

12 December 2020

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

12 December 2020

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

1 reference

12 December 2020

Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene

1 reference

12 December 2020

10.1523/JNEUROSCI.1155-15.2015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605427&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605427&resulttype=core&format=json

15 May 2020

26490873

1 reference