(Q35819806)

English

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

scientific article published on 2 September 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

molecular chaperones

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Parkinson's disease

1 reference

based on heuristic

inferred from title

10

object named as

Thomas Illig

0 references

14

object named as

Ludger Schöls

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

5

object named as

Doron Rapaport

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Alfred Nordheim

object named as

Alfred Nordheim

13

0 references

Claudia Schulte

object named as

Claudia Schulte

8

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15

object named as

Olaf Riess

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Europe PubMed Central

PMC publication ID

10 August 2017

16

object named as

Rejko Krüger

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Europe PubMed Central

PMC publication ID

10 August 2017

author name string

Lena F Burbulla

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Carina Schelling

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Hiroki Kato

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Hiroki Kato

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Dirk Woitalla

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Carola Schiesling

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Manu Sharma

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Peter Bauer

11

1 reference

Europe PubMed Central

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10 August 2017

Stephan Jung

12

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

publication date

2 September 2010

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Europe PubMed Central

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10 August 2017

Human Molecular Genetics

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Europe PubMed Central

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10 August 2017

19

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Europe PubMed Central

PMC publication ID

10 August 2017

22

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

4437-4452

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Genome-wide association study reveals genetic risk underlying Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

From proliferative to neurological role of an hsp70 stress chaperone, mortalin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Review: Familial Parkinson's disease--genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

OpenMS - an open-source software framework for mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Mortalin: a protein associated with progression of Parkinson disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

TOPP--the OpenMS proteomics pipeline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Three faces of mortalin: a housekeeper, guardian and killer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Identification of novel proteins associated with both alpha-synuclein and DJ-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Structural and functional differences between mouse mot-1 and mot-2 proteins that differ in two amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

PINK1 mutations are associated with sporadic early-onset parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Mitochondrial import and the twin-pore translocase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Neurodegeneration in normal brain aging and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Chaperones and aging: role in neurodegeneration and in other civilizational diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Probability-based protein identification by searching sequence databases using mass spectrometry data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Dissection of protein translocation across the mitochondrial outer and inner membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Mitochondrial Hsp70/MIM44 complex facilitates protein import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Correlation between complementation group for immortality and the cellular distribution of mortalin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

cDNA cloning and efficient mitochondrial import of pre-mtHSP70 from rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

A comparison of clinical and pathological features of young- and old-onset Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

Transcriptional regulation of an hsp70 heat shock gene in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

11 July 2018

CELL SIGNALING: Mitochondrial Longevity Pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Comparative proteome analyses of maize (Zea mays L.) primary roots prior to lateral root initiation reveal differential protein expression in the lateral root initiation mutantrum1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Quantitative proteomic analysis of mitochondrial proteins: relevance to Lewy body formation and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Effect of GRP75/mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

The role of pathogenic DJ-1 mutations in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Complete genomic screen in Parkinson disease: evidence for multiple genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yeast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

Elevated levels of mortalin expression in human brain tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

24 September 2018

A susceptibility gene for late-onset idiopathic Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

15 November 2018

Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298849

15 November 2018

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20817635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20817635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20817635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20817635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20817635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDQ370

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

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