(Q73349019)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

1

1 reference

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3 November 2019

Roger Reddel

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Renu Wadhwa

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

3

Kazunari Taira

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

Tomoko Yaguchi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

language of work or name

English

0 references

publication date

1 May 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

Experimental Cell Research

3 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

96-101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

Replicative senescence: an old lives' tale?

3 November 2019

cites work

1 reference

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Replicative senescence: implications for in vivo aging and tumor suppression

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Senescence and immortalization of human cells.

7 January 2021

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Switching and signaling at the telomere

7 January 2021

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Protection of mammalian telomeres

7 January 2021

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The role of senescence and immortalization in carcinogenesis

7 January 2021

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Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis

7 January 2021

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Telomere maintenance mechanisms and cellular immortalization.

7 January 2021

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Telomerase and the maintenance of chromosome ends

7 January 2021

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Telomeres, aging and cancer: in search of a happy ending

7 January 2021

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Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

7 January 2021

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Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

7 January 2021

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Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

7 January 2021

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Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

7 January 2021

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Extension of life-span by introduction of telomerase into normal human cells

7 January 2021

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Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

7 January 2021

1 reference

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Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Differential regulation of telomerase activity by six telomerase subunits

7 January 2021

1 reference

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Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Genetic and epigenetic changes in human epithelial cells immortalized by telomerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Replicative aging, telomeres, and oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

An N-terminal region of mot-2 binds to p53 in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Specific association of human telomerase activity with immortal cells and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

DNA topoisomerase inhibitors induce reversible senescence in normal human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900101-0

10.1016/S0014-4827(03)00101-0

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12729798%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference