(Q34624008)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

0 references

0 references

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

M J O'Hare

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

J Bond

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

C Clarke

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Y Takeuchi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

A J Atherton

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

C Berry

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

J Moody

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

A R Silver

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

A E Alsop

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

A M Neville

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

P S Jat

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 January 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

4 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

98

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

646-651

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 November 2019

0 references

0 references

0 references

0 references

The serial cultivation of human diploid cell strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

The establishment of telomerase-immortalized cell lines representing human chromosome instability syndromes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

7 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Human endothelial cell life extension by telomerase expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Creation of human tumour cells with defined genetic elements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Extension of life-span by introduction of telomerase into normal human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Human telomerase contains evolutionarily conserved catalytic and structural subunits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomerase catalytic subunit homologs from fission yeast and human

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Reverse transcriptase motifs in the catalytic subunit of telomerase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Analysis of proviral integration in human mammary epithelial cell lines immortalized by retroviral infection with a temperature-sensitive SV40 T-antigen construct

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

High-titer packaging cells producing recombinant retroviruses resistant to human serum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Human skin fibroblasts in vitro differentiate along a terminal cell lineage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Growth of immortal simian virus 40 tsA-transformed human fibroblasts is temperature dependent

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomeres shorten during ageing of human fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Replicative senescence: the human fibroblast comes of age.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Defining the molecular mechanisms of human cell immortalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

An oligodendrocyte precursor cell line from rat optic nerve

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Telomere length predicts replicative capacity of human fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.98.2.646

Enhanced transformation of human fibroblasts by origin-defective simian virus 40.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.98.2.646

Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14642

Risky immortalization by telomerase

26 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.98.2.646

Isolation of endothelial cells from hunan first trimester decidua using immunomagnetic beads

21 January 2018

1 reference

12 December 2020

Ectoenzyme regulation by phenotypically distinct fibroblast sub-populations isolated from the human mammary gland

1 reference

12 December 2020

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

12 December 2020

SV40-Mediated immortalization

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.98.2.646

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

11209060

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11209060%20AND%20SRC:MED&resulttype=core&format=json