(Q35825994)

10 August 2017

Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes (English)

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10 August 2017

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8

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10 August 2017

10

Atsushi Iwama

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10 August 2017

Hideyuki Oguro

1

1 reference

10 August 2017

Jin Yuan

2

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10 August 2017

Satomi Tanaka

3

1 reference

10 August 2017

Satoru Miyagi

4

1 reference

10 August 2017

Makiko Mochizuki-Kashio

5

1 reference

10 August 2017

Hitoshi Ichikawa

6

1 reference

10 August 2017

Satoshi Yamazaki

7

1 reference

10 August 2017

Hiromitsu Nakauchi

9

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10 August 2017

language of work or name

English

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publication date

20 February 2012

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Journal of Experimental Medicine

10 August 2017

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10 August 2017

209

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10 August 2017

3

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10 August 2017

445-454

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3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Role of the polycomb group proteins in hematopoietic stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Mechanisms of polycomb gene silencing: knowns and unknowns

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Stem cell regulation by polycomb repressors: postponing commitment

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Roles of HMGA proteins in cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Oncogenic HMGA2: short or small?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Use of a new adhesive film for the preparation of multi-purpose fresh-frozen sections from hard tissues, whole-animals, insects and plants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

In vitro self-renewal division of hematopoietic stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302226

Dysregulation and overexpression of HMGA2 in myelofibrosis with myeloid metaplasia

11 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111709

Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111709

Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111709

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111709

Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111709

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111709

Transforming growth factor-beta and megakaryocytes in the pathogenesis of idiopathic myelofibrosis

21 January 2018

1 reference

12 December 2020

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

1 reference

12 December 2020

Myeloproliferative disorders

1 reference

12 December 2020

Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20111709

1 reference

10 August 2017

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10 August 2017

PubMed publication ID

22351929

1 reference