(Q35827012)

English

Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs

scientific article published in June 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Sven Björkman

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 June 2005

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

59

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

691-704

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

MATURATION OF RENAL FUNCTION IN CHILDHOOD: CLEARANCE STUDIES.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Dose estimation for children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Developmental pharmacology--drug disposition, action, and therapy in infants and children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Whole body pharmacokinetic models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Physiological modeling of age-specific changes in the pharmacokinetics of organic chemicals in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Ontogeny of hepatic and renal systemic clearance pathways in infants: part II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Ontogeny of hepatic and renal systemic clearance pathways in infants: part I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Protein binding predictions in infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Maturation and growth of renal function: dosing renally cleared drugs in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Direct comparison of skin physiology in children and adults with bioengineering methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Body composition during the first 2 years of life: an updated reference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Delayed ontogenesis of CYP1A2 in the human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Adipose tissue fatty acids and size and number of fat cells from birth to 9 years of age--a cross-sectional study in 96 boys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Theophylline metabolism in human liver microsomes: inhibition studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Some suggestions for measuring predictive performance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

The pharmacokinetics of midazolam in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Pharmacokinetics of intravenous theophylline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Theophylline tissue partitioning and volume of distribution in normal and dietary-induced obese rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Aging and drug interactions. I. Effect of cimetidine and smoking on the oxidation of theophylline and cortisol in healthy men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Hepatic drug clearance in children: studies with indocyanine green as a model substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Reference values for resting blood flow to organs of man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Effects of obesity and ancillary variables (dialysis time, drug, albumin, and fatty acid concentrations) on theophylline serum protein binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Pharmacokinetics of midazolam in critically ill neonates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Relationship of theophylline clearance to oral dosage in children with chronic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Estimation and prediction of blood volume in infants and children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Pharmacokinetics of theophylline in infancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Geometric method for measuring body surface area: a height-weight formula validated in infants, children, and adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Cerebral blood flow and exchange of oxygen, glucose, ketone bodies, lactate, pyruvate and amino acids in infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

27 July 2018

Chemical changes in skeletal muscle during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

The effect of growth and function on the chemical composition of soft tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

The single-dose pharmacokinetics of midazolam and its primary metabolite in pediatric patients after oral and intravenous administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Prediction of the disposition of midazolam in surgical patients by a physiologically based pharmacokinetic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Population pharmacokinetics of midazolam in neonates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Metabolism of theophylline by cDNA-expressed human cytochromes P-450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Peripheral blood flow in the neonate; 1. Changes in total, skin, and muscle blood flow with gestational and postnatal age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Pharmacokinetics of theophylline in Ethiopian children of differing nutritional status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Effect of age, gender, and obesity on midazolam kinetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Water distribution in the foetus and newborn infant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Temporal variation in the disposition of theophylline and its metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

A pharmacokinetic study of midazolam in paediatric patients undergoing cardiac surgery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884855

24 September 2018

Nonlinear theophylline elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Adipose Tissue Composition and Age

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dependence of the renal excretion of theophylline on its plasma concentrations and urine flow rate in asthmatic children

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Body composition of reference children from birth to age 10 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the pharmacokinetics of theophylline in asthmatic children in the acute episode and in remission

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in theophylline metabolism during the first year of life

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Echo Doppler assessment of cardiac output and its relation to growth in normal infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex-related differences in theophylline pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic analysis of the disposition of intravenous theophylline in young children

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of diuretics and methylxanthines in the neonate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15948934

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2004.02225.X

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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