(Q35829141)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

NRAS mutation causes a human autoimmune lymphoproliferative syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

autoimmune lymphoproliferative syndrome

30 December 2019

main subject

0 references

author

Joao B. Oliveira

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Julie E. Niemela

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

10

Jennifer M Puck

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Nicolas Bidère

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Lixin Zheng

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Keiko Sakai

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Cynthia P Nix

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Robert L Danner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Jennifer Barb

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Peter J Munson

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Janet Dale

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Stephen E Straus

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Thomas A Fleisher

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Michael J Lenardo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

16 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

104

1 reference

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30 December 2019

issue

21

1 reference

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30 December 2019

page(s)

8953-8958

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction

30 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kappaB activation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Cancer targets in the Ras pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Compartmentalized Ras/MAPK signaling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Genetic disorders of programmed cell death in the immune system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Germline KRAS mutations cause Noonan syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Targeting the process of farynesylation for therapy of hematologic malignancies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Germline mutations in HRAS proto-oncogene cause Costello syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

The role of BH3-only proteins in the immune system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Autoimmune lymphoproliferative syndrome.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

T-lymphocyte death during shutdown of an immune response

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Autoimmune lymphoproliferative syndrome with somatic Fas mutations

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Cell death: critical control points

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

The guanine nucleotide-binding switch in three dimensions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

RAS oncogenes: the first 30 years.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885609

Mice deficient for N-ras: impaired antiviral immune response and T-cell function

24 September 2018

1 reference

12 December 2020

N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis

1 reference

12 December 2020

Immunophenotypic profiles in families with autoimmune lymphoproliferative syndrome

1 reference

12 December 2020

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0702975104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17517660%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

17517660

1 reference