(Q35833536)

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The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy

scientific article published on 5 November 2015

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy (English)

1 reference

Europe PubMed Central

10 August 2017

Alzheimer's disease

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1 reference

based on heuristic

inferred from title

author name string

Robert Siman

1

1 reference

Europe PubMed Central

10 August 2017

Ryan Cocca

2

1 reference

Europe PubMed Central

10 August 2017

Yina Dong

3

1 reference

Europe PubMed Central

10 August 2017

language of work or name

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publication date

5 November 2015

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Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

10

1 reference

Europe PubMed Central

10 August 2017

11

1 reference

Europe PubMed Central

10 August 2017

e0142340

1 reference

Europe PubMed Central

10 August 2017

copyright license

Creative Commons Attribution 4.0 International

5 November 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Neuroinflammation in Alzheimer's disease

1 reference

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11 July 2018

Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old

1 reference

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Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature

1 reference

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1 reference

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1 reference

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A rapid gene delivery-based mouse model for early-stage Alzheimer disease-type tauopathy

1 reference

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1 reference

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Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice

1 reference

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1 reference

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Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy

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Trans-synaptic spread of tau pathology in vivo

1 reference

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Fighting neurodegeneration with rapamycin: mechanistic insights

1 reference

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Autophagy failure in Alzheimer's disease--locating the primary defect

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Autophagy monitoring assay: qualitative analysis of MAP LC3-I to II conversion by immunoblot

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Pathogenic lysosomal depletion in Parkinson's disease

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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

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Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).

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12 December 2020

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10.1371/JOURNAL.PONE.0142340

1 reference

Europe PubMed Central

10 August 2017

2015PLoSO..1042340S

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1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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