(Q35845445)

English

Increased IFN-α-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-α production

scientific article published on 27 June 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Increased IFN-α-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-α production (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

type-1 diabetes

0 references

1 reference

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inferred from title

author name string

Chang-Qing Xia

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ruihua Peng

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Anna V Chernatynskaya

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Lihui Yuan

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Carolyn Carter

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

John Valentine

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Eric Sobel

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Mark A Atkinson

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Michael J Clare-Salzler

9

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Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

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publication date

27 June 2014

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Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Immunology

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Europe PubMed Central

PMC publication ID

10 August 2017

193

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1024-1034

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Molecular signatures differentiate immune states in type 1 diabetic families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Roles of pro- and anti-inflammatory cytokines in the pathogenesis of SLE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Activation of type I interferon pathway in systemic lupus erythematosus: association with distinct clinical phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The type I interferon system in the development of lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The pancreas in human type 1 diabetes: providing new answers to age-old questions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The role of Toll-like receptor pathways in the mechanism of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Innate immunity and its role in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The accelerator hypothesis and increasing incidence of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Type I interferon as a stimulus for cross-priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Cutting Edge: Antibody-mediated TLR7-dependent recognition of viral RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

CpG-B ODNs potently induce low levels of IFN-alphabeta and induce IFN-alphabeta-dependent MHC-I cross-presentation in DCs as effectively as CpG-A and CpG-C ODNs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Dendritic cells: translating innate to adaptive immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Expression of MHC II genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Control of MHC class II antigen presentation in dendritic cells: a balance between creative and destructive forces.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

A comprehensive review of interventions in the NOD mouse and implications for translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

IRF-7 is the master regulator of type-I interferon-dependent immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses--and viruses counteract IFN action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Type I interferons (alpha/beta) in immunity and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Plasmacytoid dendritic cell precursors/type I interferon-producing cells sense viral infection by Toll-like receptor (TLR) 7 and TLR9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Plasmacytoid dendritic cells in immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Interferon alpha--a potential link in the pathogenesis of viral-induced type 1 diabetes and autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Natural type I interferon-producing cells as a link between innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Dendritic cell lineage, plasticity and cross-regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Introduction: TH2-inducing DC2 for immunotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The nature of the principal type 1 interferon-producing cells in human blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Insulin-dependent diabetes mellitus during alpha-interferon therapy for chronic viral hepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

The role of type I interferons in the differentiation and function of Th1 and Th2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

11 July 2018

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

High incidence of type 1 diabetes mellitus during or shortly after treatment with pegylated interferon alpha for chronic hepatitis C virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Heightened interferon-alpha/beta response causes myeloid cell dysfunction and promotes T1D pathogenesis in NOD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes susceptibility in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Virus overrides the propensity of human CD40L-activated plasmacytoid dendritic cells to produce Th2 mediators through synergistic induction of IFN-{gamma} and Th1 chemokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Heparin induces differentiation of CD1a+ dendritic cells from monocytes: phenotypic and functional characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Fulminant autoimmune Type 1 diabetes during interferon-alpha therapy: a case of Th1-mediated disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Generation of interferon alpha-producing predendritic cell (Pre-DC)2 from human CD34(+) hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

T cell activation and polarization by DC1 and DC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4500116

24 September 2018

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating, interferon-producing plasmacytoid dendritic cells decline during human ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncover the mystery of plasmacytoid dendritic cell precursors or type 1 interferon producing cells by serendipity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of early cytokines, including alpha and beta interferons (IFN-alpha/beta), in innate and adaptive immune responses to viral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal control of T helper cell and dendritic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of interferon alpha in initiation of type I diabetes in the NOD mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: relationship with coxsackievirus B infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1303230

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

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