(Q35846700)

English

A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology

scientific article published in February 2003

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

monoclonal antibody

1 reference

based on heuristic

inferred from title

author name string

Matthew G Soars

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Harry V Gelboin

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Kristopher W Krausz

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Robert J Riley

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 February 2003

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

55

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

175-181

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

The potential pharmacological and toxicological impact of P450 screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Scaling drug biotransformation data from cDNA-expressed cytochrome P-450 to human liver: a comparison of relative activity factors and human liver abundance in studies of mirtazapine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

A monoclonal antibody inhibitory to human P450 2D6: a paradigm for use in combinatorial determination of individual P450 role in specific drug tissue metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

11 July 2018

Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

24 September 2018

Application of the relative activity factor approach in scaling from heterologously expressed cytochromes p450 to human liver microsomes: studies on amitriptyline as a model substrate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

24 September 2018

Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

24 September 2018

Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

24 September 2018

Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894739

24 September 2018

In vivo clearance of ethoxycoumarin and its prediction from In vitro systems. Use Of drug depletion and metabolite formation methods in hepatic microsomes and isolated hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human cytochrome P-450 isoforms involved in metabolism of R(+)- and S(-)-gallopamil: utility of in vitro disappearance rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory monoclonal antibodies to human cytochrome P450 1A2: analysis of phenacetin O-deethylation in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in drug metabolism screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of cytochrome P450 isoforms involved in citalopram N-demethylation by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations

1 reference

https://pubmed.ncbi.nlm.nih.gov/12580989

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2125.2003.01721.X

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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