(Q35854488)

10 August 2017

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title

RAGE: a novel target for drug intervention in diabetic vascular disease (English)

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10 August 2017

1

Barry I Hudson

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10 August 2017

2

Ann Marie Schmidt

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10 August 2017

1 July 2004

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10 August 2017

Pharmaceutical Research

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10 August 2017

21

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10 August 2017

7

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10 August 2017

1079-1086

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Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy

10 August 2017

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12 December 2020

Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease

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12 December 2020

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

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12 December 2020

RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response

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12 December 2020

Characterization of allelic and nucleotide variation between the RAGE gene on chromosome 6 and a homologous pseudogene sequence to its 5' regulatory region on chromosome 3: implications for polymorphic studies in diabetes.

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12 December 2020

Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction

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12 December 2020

Polymorphisms in the RAGE gene influence susceptibility to diabetes-associated microvascular dermatoses in NIDDM

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12 December 2020

Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes

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12 December 2020

The Functional -374 T/A RAGE Gene Polymorphism Is Associated With Proteinuria and Cardiovascular Disease in Type 1 Diabetic Patients

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12 December 2020

Effects of aminoguanidine on structural alterations of microvessels in peripheral nerve of streptozotocin diabetic rats

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12 December 2020

The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells

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12 December 2020

Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products

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12 December 2020

Advanced protein glycosylation in diabetes and aging

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12 December 2020

RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

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12 December 2020

Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications

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12 December 2020

Aminoguanidine ameliorates albuminuria in diabetic hypertensive rats

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12 December 2020

Prevention of glomerular basement membrane thickening by aminoguanidine in experimental diabetes mellitus

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12 December 2020

RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

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12 December 2020

Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice.

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12 December 2020

Expression of vascular endothelial growth factor in renal vascular disease and renal allografts

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12 December 2020

Comparative genetics of atherosclerosis and restenosis: exploration with mouse models

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12 December 2020

Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues.

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12 December 2020

Polyol and vacuole formation in cultured canine lens epithelial cells

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12 December 2020

N(epsilon)-(carboxymethyl)lysine in atherosclerotic vascular lesions as a marker for local oxidative stress

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12 December 2020

The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system

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12 December 2020

Hemoglobin components in patients with diabetes mellitus

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12 December 2020

The structure of S100A12 in a hexameric form and its proposed role in receptor signalling

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12 December 2020

Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress.

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12 December 2020

Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury

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12 December 2020

Advanced glycation end-products: a review

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12 December 2020

Cd36, a member of the class b scavenger receptor family, as a receptor for advanced glycation end products

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12 December 2020

Association of G82S polymorphism in the RAGE gene with skin complications in type 2 diabetes

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12 December 2020

A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes

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12 December 2020

Identification of polymorphisms in the receptor for advanced glycation end products (RAGE) gene: prevalence in type 2 diabetes and ethnic groups.

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12 December 2020

Effects of novel polymorphisms in the RAGE gene on transcriptional regulation and their association with diabetic retinopathy

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12 December 2020

Protein glycosylation in disease: new insights into the congenital muscular dystrophies

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12 December 2020

Metformin inhibition of glycation processes

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12 December 2020

Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways

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12 December 2020

Polymorphism screening of four genes encoding advanced glycation end-product putative receptors. Association study with nephropathy in type 1 diabetic patients

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12 December 2020

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

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12 December 2020

Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.

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12 December 2020

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

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12 December 2020

Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis

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12 December 2020

Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex

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12 December 2020

RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy

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12 December 2020

Clustering of long-term complications in families with diabetes in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group

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12 December 2020

Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy

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12 December 2020

N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression

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12 December 2020

Amadorins: novel post-Amadori inhibitors of advanced glycation reactions.

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12 December 2020

The changing face of macrovascular disease in non-insulin-dependent diabetes mellitus: an epidemic in progress.

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12 December 2020

Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking

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12 December 2020

RAGE Gly82Ser polymorphism in diabetic microangiopathy

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12 December 2020

Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats

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12 December 2020

Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy

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12 December 2020

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

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12 December 2020

Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products (AGE)

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12 December 2020

Aminoguanidine has an anti-atherogenic effect in the cholesterol-fed rabbit.

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12 December 2020

Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins

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12 December 2020

Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice

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12 December 2020

The epidemiology of cardiovascular disease in type 2 diabetes mellitus: how sweet it is ... or is it?

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12 December 2020

Genetics and molecular genetics of the MHC.

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12 December 2020

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

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12 December 2020

Maillard reaction products in tissue proteins: new products and new perspectives

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12 December 2020

Central role of RAGE-dependent neointimal expansion in arterial restenosis

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12 December 2020

Studies of an unusual hemoglobin in patients with diabetes mellitus

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12 December 2020

RAGE: a new target for the prevention and treatment of the vascular and inflammatory complications of diabetes

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12 December 2020

AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept.

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12 December 2020

Inhibitors of advanced glycation end product-associated protein cross-linking

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12 December 2020

Wound healing and diabetes mellitus

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12 December 2020

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

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12 December 2020

Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3

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12 December 2020

10.1023/B:PHAM.0000032992.75423.9B

Identifiers

DOI

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10 August 2017

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PubMed ID

15290845