(Q35855622)

10 August 2017

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title

Vascular endothelial growth factor and other signaling pathways in developmental and pathologic angiogenesis (English)

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10 August 2017

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Gavin Thurston

1

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10 August 2017

Nicholas W Gale

series ordinal

2

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10 August 2017

language of work or name

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1 July 2004

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International Journal of Hematology

10 August 2017

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10 August 2017

80

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10 August 2017

7-20

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10 August 2017

1

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https://scigraph.springernature.com/pub.10.1532/ijh97.04065

10 August 2017

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cites work

Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Abnormalities of Basement Membrane on Blood Vessels and Endothelial Sprouts in Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Endothelial cell proliferation as a novel approach to targeting tumour therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Endothelial-cell proliferation in experimental tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1532%2FIJH97.04065

Frequent epigenetic inactivation of the SLIT2 gene in gliomas

21 January 2018

1 reference

12 December 2020

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

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12 December 2020

Arteries, veins, Notch, and VEGF.

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12 December 2020

A requirement for neuropilin-1 in embryonic vessel formation.

1 reference

12 December 2020

The ultrastructure of the microcirculation at the advancing edge of Walker 256 carcinoma

1 reference

12 December 2020

Inhibition of tumor growth and metastasis by targeting tumor-associated angiogenesis with antagonists to the receptors of vascular endothelial growth factor

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12 December 2020

Interstitial fluid pressure in DMBA-induced rat mammary tumours

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12 December 2020

Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

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12 December 2020

VEGF-Trap: a VEGF blocker with potent antitumor effects

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12 December 2020

Increased tumor tissue pressure in association with the growth of rat tumors

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12 December 2020

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

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12 December 2020

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

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12 December 2020

Interstitial hypertension in superficial metastatic melanomas in humans

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12 December 2020

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

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12 December 2020

Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors

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12 December 2020

Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.

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12 December 2020

Suppression of luteal angiogenesis in the primate after neutralization of vascular endothelial growth factor

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12 December 2020

Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels

1 reference

12 December 2020

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

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12 December 2020

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

1 reference

12 December 2020

Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans

1 reference

12 December 2020

Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice.

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12 December 2020

Preclinical safety evaluation of rhuMAbVEGF, an antiangiogenic humanized monoclonal antibody

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12 December 2020

Openings between defective endothelial cells explain tumor vessel leakiness

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12 December 2020

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

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12 December 2020

Scanning and transmission electron microscopic studies on the vascular system of xenotransplanted human tumors on nude mice

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12 December 2020

Regulation of notch signaling by o-linked fucose.

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12 December 2020

Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes

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12 December 2020

Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice

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12 December 2020

Maintenance of somite borders in mice requires the Delta homologue DII1.

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12 December 2020

Regulation of signal transduction pathways in development by glycosylation

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12 December 2020

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

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12 December 2020

Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice

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12 December 2020

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

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12 December 2020

Interstitial hypertension in human breast and colorectal tumors

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12 December 2020

Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

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12 December 2020

Fringe is a glycosyltransferase that modifies Notch

1 reference

12 December 2020

Gridlock in the blood

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12 December 2020

Notch signaling in vascular development

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12 December 2020

Tumor angiogenesis: therapeutic implications

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12 December 2020

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

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12 December 2020

Blood flow and oxygenation status of human tumors. Clinical investigations

1 reference

12 December 2020

Abnormal lymphatic vessel development in neuropilin 2 mutant mice.

1 reference

12 December 2020

Defective angiogenesis in mice lacking endoglin

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12 December 2020

Node and midline defects are associated with left-right development in Delta1 mutant embryos.

1 reference

12 December 2020

Robo4 is a vascular-specific receptor that inhibits endothelial migration

1 reference

12 December 2020

A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency

1 reference

12 December 2020

Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins.

1 reference

12 December 2020

Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system

1 reference

12 December 2020

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

1 reference

12 December 2020

Structural and functional characteristics of the microcirculation in neoplasms

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12 December 2020

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

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12 December 2020

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

1 reference

12 December 2020

The vascular endothelial growth factor family of polypeptides

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12 December 2020

Notch signaling: cell fate control and signal integration in development

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12 December 2020

Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis

1 reference

12 December 2020

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

1 reference

12 December 2020

Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases

1 reference

12 December 2020

Regulation of notch signaling activity

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12 December 2020

Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

1 reference

12 December 2020

Effects of PTK787/ZK222584, a Tyrosine Kinase Inhibitor, on the Growth of a Poorly Differentiated Thyroid Carcinoma: An Animal Study

1 reference

12 December 2020

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

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12 December 2020

Angiogenesis in ischemic and neoplastic disorders

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12 December 2020

Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

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12 December 2020

Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration

1 reference

12 December 2020

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

1 reference

12 December 2020

Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity

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12 December 2020

Interstitial hypertension in head and neck tumors in patients: correlation with tumor size.

1 reference

12 December 2020

Dissecting tumour pathophysiology using intravital microscopy

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12 December 2020

A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3.

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12 December 2020

Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections.

1 reference

12 December 2020

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors

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12 December 2020

Gridlock signalling pathway fashions the first embryonic artery

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12 December 2020

In vivo and electron microscopic study of vessels in two transplantable tumours in the hamster

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12 December 2020

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

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12 December 2020

Hypoxia in neoplastic tissue

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12 December 2020

Vascular endothelial growth factor is essential for corpus luteum angiogenesis.

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12 December 2020

Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.

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12 December 2020

Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.

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12 December 2020

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

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12 December 2020

sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation

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12 December 2020

The vascular architecture of human xenotransplanted tumors: histological, morphometrical, and ultrastructural studies

1 reference

12 December 2020

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

1 reference

12 December 2020

Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model

1 reference

12 December 2020

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

1 reference

12 December 2020

Notch function in the vasculature: insights from zebrafish, mouse and man.

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12 December 2020

Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

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12 December 2020

'Accidental' anti-angiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples

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12 December 2020

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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12 December 2020

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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12 December 2020

Slit-Robo: neuronal guides signal in tumor angiogenesis

1 reference

12 December 2020

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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12 December 2020

Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model

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12 December 2020

Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy

1 reference

12 December 2020

Modification of tumor blood flow: current status and future directions

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12 December 2020

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

1 reference

12 December 2020

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

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12 December 2020

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

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12 December 2020

Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis

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12 December 2020

Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene

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12 December 2020

Genetic modifiers interact with maternal determinants in vascular development of Tgfb1(-/-) mice

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12 December 2020

Notch signaling: control of cell communication and cell fate

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12 December 2020

Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity

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12 December 2020

Hypoxia in breast cancer: pathogenesis, characterization and biological/therapeutic implications

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12 December 2020

Molecular regulation of vessel maturation

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12 December 2020

Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis

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12 December 2020

Endostatin's antiangiogenic signaling network

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12 December 2020

Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.

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12 December 2020

Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation

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12 December 2020

The proliferation of capillary endothelial cells

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12 December 2020

VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.

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12 December 2020

Congenital diaphragmatic hernia, kidney agenesis and cardiac defects associated with Slit3-deficiency in mice

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12 December 2020

Continuous low-dose anti-angiogenic/ metronomic chemotherapy: from the research laboratory into the oncology clinic

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12 December 2020

Notch signaling is essential for vascular morphogenesis in mice

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12 December 2020

Paclitaxel encapsulated in cationic liposomes diminishes tumor angiogenesis and melanoma growth in a "humanized" SCID mouse model

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12 December 2020

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

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12 December 2020

Metronomic therapy for breast cancer

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12 December 2020

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

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12 December 2020

Clinical translation of angiogenesis inhibitors

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12 December 2020

Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis

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12 December 2020

Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

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12 December 2020

RIPping notch apart: a new role for endocytosis in signal transduction?

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12 December 2020

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer

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12 December 2020

Arteriovenous malformations in mice lacking activin receptor-like kinase-1

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12 December 2020

Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways

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12 December 2020

Analysis of mural cell recruitment to tumor vessels

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12 December 2020

VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma

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12 December 2020

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12 December 2020

Notch1 is essential for postimplantation development in mice.

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12 December 2020

VEGF is required for growth and survival in neonatal mice

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12 December 2020

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.

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12 December 2020

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

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12 December 2020

Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

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12 December 2020

Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.

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12 December 2020

Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality.

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12 December 2020

Regression of established tumors and metastases by potent vascular endothelial growth factor blockade

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12 December 2020

Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration

1 reference

12 December 2020

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

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12 December 2020

Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

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12 December 2020

Transport of molecules across tumor vasculature

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12 December 2020

Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer

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12 December 2020

Identifiers

DOI

10.1532/IJH97.04065

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Dimensions Publication ID

10 August 2017

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