(Q35868311)

English

Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation

scientific article published on 20 January 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

0 references

phosphorylation

0 references

author name string

Rodrigo Orlandini de Castro

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Juan Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Jacqueline R Groves

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Emilia Alina Barbu

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Reuben P Siraganian

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

20 January 2012

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

8194-8204

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways

1 reference

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Mast cell signaling: the role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants

1 reference

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27 July 2018

Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate

1 reference

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A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

Tyrosines in the carboxyl terminus regulate Syk kinase activity and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76

1 reference

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The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells

1 reference

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Autoinhibition and adapter function of Syk.

1 reference

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Adapters in the organization of mast cell signaling

1 reference

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Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2.

1 reference

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Calcium signaling in immune cells.

1 reference

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27 July 2018

New developments in mast cell biology

1 reference

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27 July 2018

The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development

1 reference

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27 July 2018

TULA proteins regulate activity of the protein tyrosine kinase Syk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling

1 reference

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27 July 2018

Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases

1 reference

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T-cell ubiquitin ligand affects cell death through a functional interaction with apoptosis-inducing factor, a key factor of caspase-independent apoptosis

1 reference

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27 July 2018

A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

1 reference

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27 July 2018

Integrated signalling pathways for mast-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

27 July 2018

Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2

1 reference

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Mast cell signal transduction from the high-affinity IgE receptor

1 reference

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The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

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Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells

1 reference

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Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein

1 reference

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Protein tyrosine kinase Syk in mast cell signaling

1 reference

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1 reference

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Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

1 reference

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Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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SH2 domains recognize specific phosphopeptide sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

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27 July 2018

Regulation and function of syk tyrosine kinase in mast cell signaling and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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Small interfering RNA screen for phosphatases involved in IgE-mediated mast cell degranulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

24 September 2018

Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

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The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

24 September 2018

Structural basis for the inhibition of tyrosine kinase activity of ZAP-70

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

24 September 2018

The role of SHIP in mast cell degranulation and IgE-induced mast cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

24 September 2018

T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318758

24 September 2018

Selective impairment of Fc RI-mediated allergic reaction in Gads-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.326850

21 January 2018

The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22267732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SHIP negatively regulates IgE + antigen-induced IL-6 production in mast cells by inhibiting NF-kappa B activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22267732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.326850

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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