(Q35875595)

English

Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways

scientific article published in March 2004

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways (English)

1 reference

Europe PubMed Central

10 August 2017

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inferred from title

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author name string

Satya Narayan

1

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Europe PubMed Central

10 August 2017

publication date

1 March 2004

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Europe PubMed Central

10 August 2017

Journal of Molecular Histology

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Europe PubMed Central

10 August 2017

35

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Europe PubMed Central

10 August 2017

3

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Europe PubMed Central

10 August 2017

301-307

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Europe PubMed Central

10 August 2017

Beta-catenin mutations in cell lines established from human colorectal cancers

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https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation by dietary factors in murine FAP models

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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Identification of c-MYC as a target of the APC pathway

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https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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The Yin-Yang of TCF/beta-catenin signaling

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https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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Strategy and planning for chemopreventive drug development: clinical development plans II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Effect of diet on colonic-programmed cell death: molecular mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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The adenomatous polyposis coli protein and retinoblastoma protein are cleaved early in apoptosis and are potential substrates for caspases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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Regulation of complexed and free catenin pools by distinct mechanisms. Differential effects of Wnt-1 and v-Src.

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https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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Vegetables, fruit, and cancer. I. Epidemiology

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https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

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New aspects of Wnt signaling pathways in higher vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of COX-2 in intestinal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage and shedding of E-cadherin after induction of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Disruption of cell adhesion and caspase-mediated proteolysis of beta- and gamma-catenins and APC protein in paclitaxel-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt signaling and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-associated cleavage of beta-catenin in human colon cancer and rat hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of beta-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the E-cadherin/alpha-catenin complex in modulating cell-cell and cell-matrix adhesive properties of invasive colon carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of the adenomatous polyposis coli tumor suppressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Anticancer activities of curcumin on human Burkitt's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic model for colorectal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-MYC: more than just a matter of life and death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion signaling: how beta-catenin interacts with its partners

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking and suppressing mechanisms of chemoprevention by dietary constituents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cadherin adhesive activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current prospects for controlling cancer growth with non-cytotoxic agents--nutrients, phytochemicals, herbal extracts, and available drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of E- and P-cadherin during the early stages of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticancer potential of curcumin: preclinical and clinical studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and functional analysis of cadherin-based adherens junctions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and free pool of beta-catenin are regulated by tyrosine kinases and tyrosine phosphatases during epithelial cell migration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cadherin and catenin alterations in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of the adherens junctions components beta-catenin and gamma-catenin/plakoglobin during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translocations involving c-myc and c-myc function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant, gallic acid, induces apoptosis in HL-60RG cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

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Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The somatic evolution of cancer. The Harveian Oration of 1996.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell adhesion system and human cancer morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turmeric and curcumin as topical agents in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progress in cancer chemoprevention: perspectives on agent selection and short-term clinical intervention trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The evolution of cancer of the colon and rectum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of APC protein expressed by human colonic epithelial cells and the appearance of a specific low-molecular-weight form is associated with apoptosis in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:HIJO.0000032361.98815.BB

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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