(Q35876047)

10 August 2017

Sequence determinants of improved CRISPR sgRNA design (English)

1 reference

10 August 2017

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11

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10 August 2017

4

Wei Li

1 reference

10 August 2017

Han Xu

1

1 reference

10 August 2017

Tengfei Xiao

2

1 reference

10 August 2017

Chen-Hao Chen

3

1 reference

10 August 2017

Clifford A Meyer

5

1 reference

10 August 2017

Qiu Wu

6

1 reference

10 August 2017

Di Wu

7

1 reference

10 August 2017

Le Cong

8

1 reference

10 August 2017

Feng Zhang

9

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10 August 2017

Jun S Liu

10

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10 August 2017

X Shirley Liu

12

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10 August 2017

10 June 2015

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10 August 2017

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10 August 2017

25

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10 August 2017

8

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10 August 2017

1147-1157

1 reference

describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4509999/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Genome-scale CRISPR-Cas9 knockout screening in human cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Genome engineering using the CRISPR-Cas9 system

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

RNA-guided human genome engineering via Cas9

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Multiplex genome engineering using CRISPR/Cas systems

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

NIH Image to ImageJ: 25 years of image analysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Highly parallel identification of essential genes in cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

KBM-7, a human myeloid leukemia cell line with double Philadelphia chromosomes lacking normal c-ABL and BCR transcripts.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

Genetic screens in human cells using the CRISPR-Cas9 system

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

DNA targeting specificity of RNA-guided Cas9 nucleases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509999

24 September 2018

Identifiers

DOI

10.1101/GR.191452.115

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

26063738

1 reference