(Q35879478)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

Ubiquitin specific peptidase 4 (proto-oncogene)

20 January 2020

main subject

toll-like receptor

0 references

1 reference

GOA release 2020-03-11

author

Hans van Dam

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

FangFang Zhou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Xiaofei Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Peter Ten Dijke

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Huizhe Huang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Long Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

19 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

11002-11010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration.

20 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Expanding TRAF function: TRAF3 as a tri-faced immune regulator

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Direct activation of protein kinases by unanchored polyubiquitin chains

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Breaking the chains: structure and function of the deubiquitinases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

LPS response and tolerance in the zebrafish (Danio rerio)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Oncogenic protein UnpEL/Usp4 deubiquitinates Ro52 by its isopeptidase activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Negative regulation of toll-like receptor-mediated immune responses

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Toll-like receptor signalling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Toll-like receptor signaling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Innate immune recognition

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Tumor necrosis factor receptor-associated factors (TRAFs)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Toll-like receptors: critical proteins linking innate and acquired immunity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Activators and target genes of Rel/NF-kappaB transcription factors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

A ubiquitin-specific protease that efficiently cleaves the ubiquitin-proline bond.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

The Unp proto-oncogene encodes a nuclear protein.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322833

USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation

11 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.328187

The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22262844

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toll-like receptor signaling pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22262844

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vectors and techniques for ectopic gene expression in zebrafish

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22262844

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.328187

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22262844%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference