(Q35881879)

English

Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activation

scientific article published on 14 March 2012

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activation (English)

1 reference

Europe PubMed Central

10 August 2017

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1 reference

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inferred from title

8

object named as

Laurie Erb

1 reference

Europe PubMed Central

10 August 2017

author name string

Hye Jung Kim

1

1 reference

Europe PubMed Central

10 August 2017

Deepa Ajit

2

1 reference

Europe PubMed Central

10 August 2017

Troy S Peterson

3

1 reference

Europe PubMed Central

10 August 2017

Yanfang Wang

4

1 reference

Europe PubMed Central

10 August 2017

Jean M Camden

5

1 reference

Europe PubMed Central

10 August 2017

W Gibson Wood

6

1 reference

Europe PubMed Central

10 August 2017

Grace Y Sun

7

1 reference

Europe PubMed Central

10 August 2017

Michael Petris

9

1 reference

Europe PubMed Central

10 August 2017

Gary A Weisman

10

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Europe PubMed Central

10 August 2017

language of work or name

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publication date

14 March 2012

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Europe PubMed Central

10 August 2017

Journal of Neurochemistry

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Europe PubMed Central

10 August 2017

121

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Europe PubMed Central

10 August 2017

228-238

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Europe PubMed Central

10 August 2017

2

1 reference

Europe PubMed Central

10 August 2017

Age-related alterations in the dynamic behavior of microglia

1 reference

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Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides (i).

1 reference

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Neuroglial ATP release through innexin channels controls microglial cell movement to a nerve injury

1 reference

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Altered microglial copper homeostasis in a mouse model of Alzheimer's disease

1 reference

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Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

1 reference

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Amyloid-beta(1-42) fibrillar precursors are optimal for inducing tumor necrosis factor-alpha production in the THP-1 human monocytic cell line

1 reference

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Modulation of the ATP-lnduced release and processing of IL-1beta in microglial cells

1 reference

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Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor

1 reference

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Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance

1 reference

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

1 reference

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ATP released from beta-amyloid-stimulated microglia induces reactive oxygen species production in an autocrine fashion

1 reference

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In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brain

1 reference

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Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

11 July 2018

The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.

1 reference

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Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives

1 reference

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Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

1 reference

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Inflammation and neurodegenerative diseases

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Dissociation of recruitment and activation of the small G-protein Rac during Fcgamma receptor-mediated phagocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

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The P2Y2 nucleotide receptor interacts with alphav integrins to activate Go and induce cell migration.

1 reference

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ATP mediates rapid microglial response to local brain injury in vivo

1 reference

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Mechanisms of cell signaling and inflammation in Alzheimer's disease

1 reference

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11 July 2018

P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

11 July 2018

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

11 July 2018

Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism.

1 reference

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Immunotherapeutic Approaches to Alzheimer's Disease

1 reference

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A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

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In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

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Functional P2Y2 nucleotide receptors mediate uridine 5'-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

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Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

1 reference

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Nucleotide receptors involved in UTP-induced rat arterial smooth muscle cell migration

1 reference

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Purinergic signalling: ATP release

1 reference

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An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction

1 reference

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Inflammation and Alzheimer's disease

1 reference

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P2Y receptors in the nervous system: molecular studies of a P2Y2 receptor subtype from NG108-15 neuroblastoma x glioma hybrid cells

1 reference

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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Mechanical stress induces release of ATP from Ehrlich ascites tumor cells.

1 reference

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Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia

1 reference

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Amyloid-beta induces chemokine secretion and monocyte migration across a human blood--brain barrier model

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Overexpression of P2Y2 purinoceptor in intimal lesions of the rat aorta

1 reference

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Microglial response to amyloid plaques in APPsw transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323761

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Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes

1 reference

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Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

1 reference

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Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein

1 reference

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Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils.

1 reference

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Activation of microglia by amyloid {beta} requires P2X7 receptor expression

1 reference

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Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain.

1 reference

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Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

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P2Y nucleotide receptor interaction with alpha integrin mediates astrocyte migration

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Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice.

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Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia.

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Origin and turnover of microglial cells in fibrillar plaques of APPsw transgenic mice.

1 reference

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

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ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels.

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The leukocyte-common antigen (CD45) complex and B-lymphocyte activation

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https://pubmed.ncbi.nlm.nih.gov/22353164

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Mechanisms by which extracellular ATP and UTP stimulate the release of prostacyclin from bovine pulmonary artery endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22353164

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Release of ATP from human erythrocytes in response to a brief period of hypoxia and hypercapnia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22353164

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Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways

1 reference

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Identifiers

10.1111/J.1471-4159.2012.07700.X

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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