(Q35892062)

11 August 2017

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title

Diagnosing prion diseases: needs, challenges and hopes (English)

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11 August 2017

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Claudio Soto

1

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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Nature Reviews Microbiology

11 August 2017

published in

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11 August 2017

volume

2

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11 August 2017

issue

10

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11 August 2017

page(s)

809-819

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Rapid test for the preclinical postmortem diagnosis of BSE in central nervous system tissue.

11 August 2017

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Quantitative analysis of MRI signal intensity in new variant Creutzfeldt-Jakob disease

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31 March 2020

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Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

31 March 2020

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Infectious diseases. Uncertainties plague projections of vCJD toll

31 March 2020

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Prions and the immune system: a journey through gut, spleen, and nerves

31 March 2020

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Pathogenesis of scrapie in mice after intragastric infection

31 March 2020

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Passage of murine scrapie prion protein across the mouse vascular blood-brain barrier

31 March 2020

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Putting prions to the test.

31 March 2020

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BSE and prions: uncertainties about the agent

31 March 2020

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The controversial protein-only hypothesis of prion propagation.

31 March 2020

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Is the scrapie agent a virus?

31 March 2020

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The exceptionally small size of the scrapie agent

31 March 2020

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Scrapie agent unlike viruses in size and susceptibility to inactivation by ionizing or ultraviolet radiation

31 March 2020

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Identification of a protein that purifies with the scrapie prion.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Immunoaffinity purification and neutralization of scrapie prion infectivity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

31 March 2020

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Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Pathologic conformations of prion proteins

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Interactions and conversions of prion protein isoforms

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Cell-free formation of protease-resistant prion protein.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Cyclic amplification of protein misfolding: application to prion-related disorders and beyond

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Synthetic mammalian prions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Blood infectivity and the prospects for a diagnostic screening test in Creutzfeldt-Jakob disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Recent advances in the pre-mortem diagnosis of Creutzfeldt-Jakob disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Molecular diagnostics of transmissible spongiform encephalopathies

31 March 2020

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Diagnosis of Creutzfeldt-Jakob disease and related human spongiform encephalopathies

31 March 2020

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Clinical features of variant Creutzfeldt-Jakob disease

31 March 2020

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Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Gerstmann-Sträussler-Scheinker disease and the Indiana kindred

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Fatal familial insomnia: clinical features and molecular genetics

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

High levels of nervous system-specific proteins in cerebrospinal fluid in patients with early stage Creutzfeldt-Jakob disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

A novel erythroid-specific marker of transmissible spongiform encephalopathies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Transcript level of erythroid differentiation-related factor, a candidate surrogate marker for transmissible spongiform encephalopathy diseases in blood, shows a broad range of variation in healthy individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

European Union's rapid TSE testing in adult cattle and sheep: implementation and results in 2001 and 2002.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Brussels seeks BSE diagnostic test to screen European cattle

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

31 March 2020

Tests for BSE evaluated

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Validation of a western immunoblotting procedure for bovine PrP(Sc) detection and its use as a rapid surveillance method for the diagnosis of bovine spongiform encephalopathy (BSE).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Screening slaughtered cattle for BSE

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Validation of a luminescence immunoassay for the detection of PrP(Sc) in brain homogenate.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Eight prion strains have PrP(Sc) molecules with different conformations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Predicting the CJD epidemic in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

31 March 2020

Testing times for BSE.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Extending backcalculation to analyse BSE data

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Transmission of BSE by blood transfusion in sheep

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt-Jakob disease in humans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Interventional strategies against prion diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Approaches to prophylaxis and therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Therapeutic approaches to prion diseases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Rapid diagnosis of scrapie in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Mouse models of prion disease transmission

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Early detection of PrPres in BSE-infected bovine PrP transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Preclinical test for prion diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Prevalence of lymphoreticular prion protein accumulation in UK tissue samples.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Detection of pathologic prion protein in the olfactory epithelium in sporadic Creutzfeldt-Jakob disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

A protease-resistant prion protein isoform is present in urine of animals and humans affected with prion diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

A pitfall in diagnosis of human prion diseases using detection of protease-resistant prion protein in urine. Contamination with bacterial outer membrane proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Antigenic features of prion proteins of sheep and of other mammalian species

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

New insight into abnormal prion protein using monoclonal antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Immunodiagnosis of prion disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Prion (PrPSc)-specific epitope defined by a monoclonal antibody

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Monoclonal antibodies specific for the native, disease-associated isoform of the prion protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

A prion protein epitope selective for the pathologically misfolded conformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Monoclonal antibody against a peptide of human prion protein discriminates between Creutzfeldt-Jacob's disease-affected and normal brain tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Antibody to DNA detects scrapie but not normal prion protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Detection and discrimination of PrPSc by multi-spectral ultraviolet fluorescence.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Antemortem identification of bovine spongiform encephalopathy from serum using infrared spectroscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Molecular changes of preclinical scrapie can be detected by infrared spectroscopy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

A diagnostic test for scrapie-infected sheep using a capillary electrophoresis immunoassay with fluorescent-labeled peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Use of capillary electrophoresis and fluorescent labeled peptides to detect the abnormal prion protein in the blood of animals that are infected with a transmissible spongiform encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Analysis of the performance of antibody capture methods using fluorescent peptides with capillary zone electrophoresis with laser-induced fluorescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Failure of immunocompetitive capillary electrophoresis assay to detect disease-specific prion protein in buffy coat from humans and chimpanzees with Creutzfeldt-Jakob disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Binding of disease-associated prion protein to plasminogen.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Plasminogen binds to disease-associated prion protein of multiple species.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

The fate of the prion protein in the prion/plasminogen complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

The binding of prion proteins to serum components is affected by detergent extraction conditions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

RNA molecules stimulate prion protein conversion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

The prion protein has RNA binding and chaperoning properties characteristic of nucleocapsid protein NCP7 of HIV-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Prion-protein-specific aptamer reduces PrPSc formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Structural determinants of conformationally selective, prion-binding aptamers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Cultured cell sublines highly susceptible to prion infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Creutzfeldt-Jakob disease: blood infectivity and screening tests

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

The distribution of infectivity in blood components and plasma derivatives in experimental models of transmissible spongiform encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Scrapie infectivity in hamster blood is not associated with platelets.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Protein misfolding and disease; protein refolding and therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

31 March 2020

Conformational disease

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

31 March 2020

Identifiers

DOI

10.1038/NRMICRO1003

1 reference

11 August 2017

1 reference