(Q35122351)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

review article

1 reference

title

Therapeutic approaches to prion diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Fabrizio Tagliavini

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

Giacomina Rossi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Gianluigi Forloni

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Orso Bugiani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

publication date

1 March 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

Clinics in laboratory medicine

3 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

187-208

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

Scrapie prions aggregate to form amyloid-like birefringent rods

3 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Novel proteinaceous infectious particles cause scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Eight prion strains have PrP(Sc) molecules with different conformations

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Chemoprophylaxis of scrapie in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Dextran Sulphate 500 Delays and Prevents Mouse Scrapie by Impairment of Agent Replication in Spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Prolongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Suppression of scrapie infection in mice by heteropolyanion 23, dextran sulfate, and some other polyanions

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

The antiviral compound HPA-23 can prevent scrapie when administered at the time of infection

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Studies of the lymphoreticular system in the pathogenesis of scrapie: The role of spleen and thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Scrapie: Effect of Dh gene on incubation period of extraneurally injected agent

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Immune system-dependent and -independent replication of the scrapie agent

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Levels of infectivity in the blood throughout the incubation period of hamsters peripherally injected with scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Characterization and polyanion-binding properties of purified recombinant prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Synthesis and trafficking of prion proteins in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Heparan sulfate proteoglycan is associated with amyloid plaques and neuroanatomically targeted PrP pathology throughout the incubation period of scrapie-infected mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Sulfated glycosaminoglycans in amyloid plaques of prion diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Inhibition of scrapie-associated PrP accumulation. Probing the role of glycosaminoglycans in amyloidogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Amphotericin B: a novel class of antiscrapie drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Measurement of the concentration of amphotericin B in brain tissue of scrapie-infected hamsters with a simple and sensitive method

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

MS-8209, a water-soluble amphotericin B derivative, affects both scrapie agent replication and PrPres accumulation in Syrian hamster scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Pharmacological studies of a new derivative of amphotericin B, MS-8209, in mouse and hamster scrapie.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Late treatment with polyene antibiotics can prolong the survival time of scrapie-infected animals

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Failure to ameliorate Creutzfeldt-Jakob disease with amphotericin B therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Inhibiting scrapie neuroinvasion by polyene antibiotic treatment of SCID mice

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Effect of amphotericin B on wild-type and mutated prion proteins in cultured cells: putative mechanism of action in transmissible spongiform encephalopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Amphotericin B: new life for an old drug

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

The endocytic process in CHO cells, a toxic pathway of the polyene antibiotic amphotericin B.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Differential effects of a new amphotericin B derivative, MS-8209, on mouse BSE and scrapie: implications for the mechanism of action of polyene antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Levels and distributions of phospholipids and cholesterol in the plasma membrane of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

1 reference

7 January 2021

Amyloid deposits and amyloidosis: the beta-fibrilloses (second of two parts).

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Potent inhibition of scrapie-associated PrP accumulation by congo red

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Supramolecular ligands: monomer structure and protein ligation capability.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Cell-free formation of protease-resistant prion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Scrapie amyloid (prion) protein has the conformational characteristics of an aggregated molten globule folding intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

The anti-prion activity of Congo red. Putative mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Internal exposure of rats to benzidine derived from orally administered benzidine-based dyes after intestinal azo reduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Screening Congo Red and its analogues for their ability to prevent the formation of PrP-res in scrapie-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Effectiveness of anthracycline against experimental prion disease in Syrian hamsters.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Tetracyclines affect prion infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Porphyrin and phthalocyanine antiscrapie compounds.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Protein misfolding and disease; protein refolding and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Elimination of prions by branched polyamines and implications for therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Branched polyamines cure prion-infected neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Inactivation of the scrapie agent by ultraviolet irradiation in the presence of chlorpromazine

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Immunoaffinity purification and neutralization of scrapie prion infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Prion diseases and the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Vaccination with an attenuated Creutzfeldt-Jakob disease strain prevents expression of a virulent agent

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Modulation of proteinase-K resistant prion protein by prion peptide immunization.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Complement facilitates early prion pathogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

A role for complement in transmissible spongiform encephalopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Mimicking dominant negative inhibition of prion replication through structure-based drug design

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Novel approaches in diagnosis and therapy of Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Suppression of PrP(Sc)- and HIV-1 gp120 induced neuronal cell death by sulfated colominic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Evolution of a strain of CJD that induces BSE-like plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Dapsone to delay symptoms in Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

Early behavioural changes in scrapie-affected mice and the influence of dapsone

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900042-2

7 January 2021

10.1016/S0272-2712(02)00042-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12733432%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference