(Q35893349)

English

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells

scientific article published on 6 November 2008

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells (English)

1 reference

Europe PubMed Central

11 August 2017

0 references

molecular chaperones

0 references

1 reference

based on heuristic

inferred from title

Kai Kaarniranta

15

1 reference

Europe PubMed Central

11 August 2017

Eeva-Liisa Eskelinen

12

object named as

Eeva-Liisa Eskelinen

0 references

13

object named as

Hannu Uusitalo

1 reference

Europe PubMed Central

11 August 2017

Carina I Holmberg

object named as

Carina I Holmberg

8

0 references

object named as

Kirsi Rilla

4

0 references

object named as

Seppo Meri

10

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author name string

Tuomas Ryhänen

1

1 reference

Europe PubMed Central

11 August 2017

Juha M T Hyttinen

2

1 reference

Europe PubMed Central

11 August 2017

Jürgen Kopitz

3

1 reference

Europe PubMed Central

11 August 2017

Erkki Kuusisto

5

1 reference

Europe PubMed Central

11 August 2017

Eliisa Mannermaa

6

1 reference

Europe PubMed Central

11 August 2017

Johanna Viiri

7

1 reference

Europe PubMed Central

11 August 2017

Ilkka Immonen

9

1 reference

Europe PubMed Central

11 August 2017

Jussi Parkkinen

11

1 reference

Europe PubMed Central

11 August 2017

Antero Salminen

14

1 reference

Europe PubMed Central

11 August 2017

publication date

6 November 2008

1 reference

Europe PubMed Central

11 August 2017

Journal of Cellular and Molecular Medicine

1 reference

Europe PubMed Central

11 August 2017

13

1 reference

Europe PubMed Central

11 August 2017

3616-3631

1 reference

Europe PubMed Central

11 August 2017

9B

1 reference

Europe PubMed Central

11 August 2017

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Autophagy, organelles and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The roles of intracellular protein-degradation pathways in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Maturation of autophagic vacuoles in Mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Protein degradation and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Autophagy in health and disease: a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Autophagy: many paths to the same end.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Inefficient degradation of truncated polyglutamine proteins by the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Autophagy: in sickness and in health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Inhibition of Hsp90: a new strategy for inhibiting protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Age-Related Macular Degeneration: Etiology, Pathogenesis, and Therapeutic Strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

At the acidic edge: emerging functions for lysosomal membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Lipofuscin: mechanisms of age-related accumulation and influence on cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Regulation of apoptosis by the ubiquitin and proteasome pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The role of the retinal pigment epithelium: topographical variation and ageing changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Aggresomes, inclusion bodies and protein aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The chaperone function of hsp70 is required for protection against stress-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Senescence of the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The ubiquitin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Intracellular protein degradation in mammalian and bacterial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

Pathophysiology of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

High efficiency transformation of Escherichia coli with plasmids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

27 July 2018

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

Neuronal cells show regulatory differences in the hsp70 gene response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

Inhibition of RPE lysosomal and antioxidant activity by the age pigment lipofuscin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

How do intracellular proteolytic systems change with age?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4516511

24 September 2018

Proteolysis: from the lysosome to ubiquitin and the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19017362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Lipid Peroxidation-Related Protein Modifications on RPE Lysosomal Functions and POS Phagocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19017362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19017362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time, stress, and location dependent chondrocyte death and collagen damage in cyclically loaded articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19017362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/19017362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19017362

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1582-4934.2008.00577.X

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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