(Q35911136)

11 August 2017

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title

Regulation of MMP-9 gene expression for the development of novel molecular targets against cancer and inflammatory diseases (English)

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11 August 2017

Yves St-Pierre

1

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11 August 2017

Julie Couillard

series ordinal

2

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11 August 2017

Céline Van Themsche

series ordinal

3

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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Expert Opinion on Therapeutic Targets

11 August 2017

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11 August 2017

8

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11 August 2017

5

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11 August 2017

473-489

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11 August 2017

Inflammation and cancer

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Interferons inhibit tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 activation via interferon regulatory factor-1 binding competition with NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Shortening of microsatellite deoxy(CA) repeats involved in GL331-induced down-regulation of matrix metalloproteinase-9 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Protein kinase C isozymes and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Protein kinase C-alpha modulates lipopolysaccharide-induced functions in a murine macrophage cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

High levels of gelatinase-B and active gelatinase-A in metastatic glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

I kappa B proteins: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Review of the biology of Quercetin and related bioflavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

How MAP kinases are regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Sounding the alarm: protein kinase cascades activated by stress and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

HIV-1 glycoprotein 120 induces the MMP-9 cytopathogenic factor production that is abolished by inhibition of the p38 mitogen-activated protein kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

ERK1/2 mediates TNF-alpha-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-kappaB and AP-1: Involvement of the ras dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-α in human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Laminin SIKVAV peptide induction of monocyte/macrophage prostaglandin E2 and matrix metalloproteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Synthesis of the active metabolite of vitamin D, 1,25(OH)2D3, by synovial fluid macrophages in arthritic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Suppression of the functionally coupled cyclooxygenase-2/prostaglandin E synthase as a basis of simvastatin-dependent plaque stabilization in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Gene silencing in cancer in association with promoter hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

DNA methylation, chromatin inheritance, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

DNA methylation in haematological malignancies: the role of decitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Prodrugs for Gene-Directed Enzyme-Prodrug Therapy (Suicide Gene Therapy)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-alpha induced morphological change of human endothelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Inhibition of MMP-9 expression by PPARgamma activators in human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

U0126, a mitogen-activated protein kinase kinase inhibitor, inhibits the invasion of human A375 melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Activation of protein kinase Czeta is essential for cytokine-induced metalloproteinase-1, -3, and -9 secretion from rabbit smooth muscle cells and inhibits proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Induction of matrix metalloproteinase-9 requires a polymerized actin cytoskeleton in human malignant glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

The integrin linked kinase (ILK) induces an invasive phenotype via AP-1 transcription factor-dependent upregulation of matrix metalloproteinase 9 (MMP-9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Chemokine stimulation of monocyte matrix metalloproteinase-9 requires endogenous TNF-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Angiopoietin/Tek Interactions Regulate MMP-9 Expression and Retinal Neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Secretion of matrix metalloproteinase-9 by the proinflammatory cytokine, IL-1beta: a role for the dual signalling pathways, Akt and Erk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Mitogen-activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP-9) in breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Time course for inhibition of lipopolysaccharide-induced lung injury by genistein: relationship to alteration in nuclear factor-kB activity and inflammatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Malolactomycin D, a potent inhibitor of transcription controlled by the Ras responsive element, inhibits Ras-mediated transformation activity with suppression of MMP-1 and MMP-9 in NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Secretory leukocyte protease inhibitor suppresses the production of monocyte prostaglandin H synthase-2, prostaglandin E2, and matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

PTEN induces G1 cell cycle arrest and inhibits MMP-9 expression via the regulation of NF-kappaB and AP-1 in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Quercetin exerts multiple inhibitory effects on vascular smooth muscle cells: role of ERK1/2, cell-cycle regulation, and matrix metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Polymorphism in matrix metalloproteinase gene promoters: implication in regulation of gene expression and susceptibility of various diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.473

21 January 2018

Identifiers

DOI

10.1517/14728222.8.5.473

1 reference

11 August 2017

1 reference