(Q35916092)

11 August 2017

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo (English)

1 reference

11 August 2017

25

Christof von Kalle

0 references

Martijn Brugman

Martijn H Brugman

4

0 references

Kimberly Gilmour

Kimberly C Gilmour

13

0 references

Adrian Thrasher

Adrian J Thrasher

24

0 references

Manfred Schmidt

3

Manfred Schmidt

1 reference

11 August 2017

22

Gerard Wagemaker

1 reference

11 August 2017

23

H Bobby Gaspar

1 reference

11 August 2017

15

Jinhua Bayford

1 reference

11 August 2017

5

Annette Deichmann

1 reference

11 August 2017

Kerstin Schwarzwaelder

1

Kerstin Schwarzwaelder

1 reference

11 August 2017

6

Hanno Glimm

1 reference

11 August 2017

9

Manuela Wissler

1 reference

11 August 2017

12

Kathryn L Parsley

1 reference

11 August 2017

17

Karin Pike-Overzet

1 reference

11 August 2017

18

Frank J T Staal

1 reference

11 August 2017

19

Dick de Ridder

1 reference

11 August 2017

21

Ulrich Abel

1 reference

11 August 2017

Steven J Howe

2

1 reference

11 August 2017

Sonja Schmidt

7

1 reference

11 August 2017

Claudia Prinz

8

1 reference

11 August 2017

Douglas J S King

10

1 reference

11 August 2017

Fang Zhang

11

1 reference

11 August 2017

Joanna Sinclair

14

1 reference

11 August 2017

Rachel Peraj

16

1 reference

11 August 2017

Christine Kinnon

20

1 reference

11 August 2017

language of work or name

English

0 references

publication date

1 August 2007

1 reference

Journal of Clinical Investigation

11 August 2017

1 reference

11 August 2017

117

1 reference

11 August 2017

8

1 reference

11 August 2017

2241-2249

1 reference

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Targeting survival: integration site selection by retroviruses and LTR-retrotransposons

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Transcription start regions in the human genome are favored targets for MLV integration

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

HIV-1 integration in the human genome favors active genes and local hotspots

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Factors affecting long-term stability of Moloney murine leukemia virus-based vectors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoter

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Polyclonal long-term repopulating stem cell clones in a primate model

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934556

Murine leukemia induced by retroviral gene marking

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17671654

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New genes involved in cancer identified by retroviral tagging

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17671654

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI31661

1 reference

11 August 2017

1 reference

11 August 2017

1 reference