(Q35917450)

English

A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development.

scientific article published on 15 June 2015

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scholarly article

1 reference

Europe PubMed Central

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17 February 2020

A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development (English)

1 reference

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17 February 2020

2

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17 February 2020

Andrés J López-Contreras

3

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17 February 2020

Óscar Fernández-Capetillo

4

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17 February 2020

1

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Julia Specks

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17 February 2020

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publication date

15 June 2015

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17 February 2020

Molecular and Cellular Biology

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17 February 2020

35

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17 February 2020

17

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17 February 2020

2910-2917

1 reference

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17 February 2020

ERCC1 and RRM1: ready for prime time?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

27 July 2018

Nucleotide deficiency promotes genomic instability in early stages of cancer development

1 reference

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27 July 2018

The ATR barrier to replication-born DNA damage.

1 reference

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27 July 2018

Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools

1 reference

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27 July 2018

The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage

1 reference

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27 July 2018

ATR: an essential regulator of genome integrity

1 reference

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Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase.

1 reference

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27 July 2018

Ribonucleotide reductases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

27 July 2018

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

1 reference

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27 July 2018

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

27 July 2018

Yeast Sml1, a protein inhibitor of ribonucleotide reductase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

27 July 2018

A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

27 July 2018

The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

27 July 2018

Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

A functional approach reveals a genetic and physical interaction between ribonucleotide reductase and CHK1 in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

Replication stress and cancer: it takes two to tango.

1 reference

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24 September 2018

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

DNA precursor metabolism and genomic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

A ribonucleotide reductase gene is a transcriptional target of p53 and p73

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

Mutator phenotypes in mammalian cell mutants with distinct biochemical defects and abnormal deoxyribonucleoside triphosphate pools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525308

24 September 2018

IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26077802

12 December 2020

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Identifiers

10.1128/MCB.00475-15

1 reference

Europe PubMed Central

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17 February 2020

release_uhz4iy5yf5av5mi4xjj54lmo6u

1 reference

https://api.fatcat.wiki/v0/release/uhz4iy5yf5av5mi4xjj54lmo6u

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Europe PubMed Central

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17 February 2020

1 reference

Europe PubMed Central

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17 February 2020

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