(Q35920095)

English

E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas

scientific article published in September 2003

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Ulrike Ziebold

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Eunice Y Lee

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Roderick T Bronson

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Jacqueline A Lees

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

1 September 2003

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

6542-6552

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

E2f3 is critical for normal cellular proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

The regulation of E2F by pRB-family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Distinct roles for E2F proteins in cell growth control and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Cancer cell cycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

The retinoblastoma protein binds to a family of E2F transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Structural evidence for the authenticity of the human retinoblastoma gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

The retinoblastoma gene and gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Requirement for a functional Rb-1 gene in murine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Effects of an Rb mutation in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

27 July 2018

Inactivation of E2F3 results in centrosome amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

E2F4 loss suppresses tumorigenesis in Rb mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Sibling rivalry in the E2F family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

The E2F1-3 transcription factors are essential for cellular proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Haplo-insufficiency? Let me count the ways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

E2F4 is essential for normal erythrocyte maturation and neonatal viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Accommodating haploinsufficient tumor suppressor genes in Knudson's model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

The retinoblastoma gene family: cousins with overlapping interests

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=193688

24 September 2018

Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility to tumors induced in mice by ethylnitrosourea is independent of retinoblastoma gene dosage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of heterozygosity for the Rb-1t19neo allele in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for E2F1 in the induction of apoptosis during thymic negative selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of E2F2 in Mice Causes Enhanced T Lymphocyte Proliferation, Leading to the Development of Autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARF is not required for apoptosis in Rb mutant mouse embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/12944480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.23.18.6542-6552.2003

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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