(Q35929315)

English

Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway

scientific article published on 8 March 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Arthur I Cederbaum

2

object named as

Arthur I Cederbaum

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Aparajita Dey

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

8 March 2007

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Archives of Biochemistry and Biophysics

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

461

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

275-286

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

CAGE, a novel cancer/testis antigen gene, promotes cell motility by activation ERK and p38 MAPK and downregulating ROS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

An analog of a dipeptide-like structure of FK506 increases glial cell line-derived neurotrophic factor expression through cAMP response element-binding protein activated by heat shock protein 90/Akt signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

HSP90 and the chaperoning of cancer

1 reference

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2 October 2017

Interaction between the 90-kDa heat shock protein and soluble guanylyl cyclase: physiological significance and mapping of the domains mediating binding

1 reference

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2 October 2017

Mitochondria-to-nucleus stress signaling in mammalian cells: nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis

1 reference

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2 October 2017

A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors.

1 reference

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2 October 2017

Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

1 reference

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2 October 2017

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

1 reference

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2 October 2017

Hsp90 isoforms: functions, expression and clinical importance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Inhibition of Hsp90: a new strategy for inhibiting protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Hsp70 and Hsp90--a relay team for protein folding

1 reference

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2 October 2017

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

1 reference

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2 October 2017

Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Heat-shock protein 90, a chaperone for folding and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

CYP2E1-dependent toxicity and oxidative stress in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Chaperones in cell cycle regulation and mitogenic signal transduction: a review

1 reference

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2 October 2017

Heat-shock proteins as death determinants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Hsp90 & Co. - a holding for folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

The Hsp70 and Hsp60 chaperone machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

Molecular chaperones in cellular protein folding

1 reference

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2 October 2017

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

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2 October 2017

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

2 October 2017

RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

11 July 2018

Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1.

1 reference

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11 July 2018

Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection

1 reference

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24 September 2018

c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production

1 reference

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24 September 2018

Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

24 September 2018

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

24 September 2018

Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

24 September 2018

Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

24 September 2018

Mitochondria as regulators of apoptosis: doubt no more.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

24 September 2018

Bcl-2 Phosphorylation by p38 MAPK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

14 November 2018

Hsp90 Recognizes a Common Surface on Client Kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1942044

14 November 2018

CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90

1 reference

https://pubmed.ncbi.nlm.nih.gov/17382893

12 December 2020

based on heuristic

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Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17382893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cytochrome P4502E1 in alcoholic liver disease pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17382893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17382893

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Molecular chaperones: biology and prospects for pharmacological intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/17382893

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.ABB.2007.02.014

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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