(Q40472339)

English

A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors.

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scholarly article

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Europe PubMed Central

PubMed publication ID

20 September 2017

A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors. (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

toll-like receptor

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molecular chaperones

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Eric C. Reynolds

6

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Andrew J Fleetwood

object named as

Andrew J Fleetwood

5

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Dominic De Nardo

object named as

Dominic De Nardo

1

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John A. Hamilton

object named as

John A Hamilton

7

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author name string

Paul Masendycz

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Sokwei Ho

3

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Europe PubMed Central

PubMed publication ID

20 September 2017

Maddalena Cross

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Glen M Scholz

8

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

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publication date

12 January 2005

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Europe PubMed Central

PubMed publication ID

20 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

20 September 2017

280

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Europe PubMed Central

PubMed publication ID

20 September 2017

11

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Europe PubMed Central

PubMed publication ID

20 September 2017

9813-9822

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Europe PubMed Central

PubMed publication ID

20 September 2017

Innate immune recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

How we detect microbes and respond to them: the Toll-like receptors and their transducers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Regulation of IL-1 receptor-associated kinases by lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Negative regulation of toll-like receptor-mediated signaling by Tollip

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Steroid receptor interactions with heat shock protein and immunophilin chaperones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Hop modulates Hsp70/Hsp90 interactions in protein folding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Cdc37 is a molecular chaperone with specific functions in signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Tolerance to pyrogens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Functional Dissection of Cdc37: Characterization of Domain Structure and Amino Acid Residues Critical for Protein Kinase Binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Role of the heat shock protein 90 in immune response stimulation by bacterial DNA and synthetic oligonucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Geldanamycin inhibits the production of inflammatory cytokines in activated macrophages by reducing the stability and translation of cytokine transcripts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Geldanamycin treatment ameliorates the response to LPS in murine macrophages by decreasing CD14 surface expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Bacterial lipopolysaccharide induces expression of the stress response genes hop and H411.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alterations in IL-1 receptor-associated kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409745200

21 January 2018

Identifiers

10.1074/JBC.M409745200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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