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Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
editorial
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title
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
main subject
mitotic checkpoint complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0033597
author
Laura A Díaz-Martínez
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
author name string
Hongtao Yu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
24 July 2007
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
published in
Cell Division
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
page(s)
23
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
exact match
https://scigraph.springernature.com/pub.10.1186/1747-1028-2-23
0 references
cites work
Cdc20: a WD40 activator for a cell cycle degradation machine
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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
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2 October 2017
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2 October 2017
Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint
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2 October 2017
Dual inhibition of Cdc20 by the spindle checkpoint
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2 October 2017
Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint
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2 October 2017
Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint
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2 October 2017
Mitotic regulation of the anaphase-promoting complex
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2 October 2017
APC/C--the master controller of origin licensing?
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The APC/C inhibitor, Emi1, is essential for prevention of rereplication
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Does aneuploidy cause cancer?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The anaphase promoting complex/cyclosome: a machine designed to destroy
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PubMed Central
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2 October 2017
Polo-like kinase 1: target and regulator of anaphase-promoting complex/cyclosome-dependent proteolysis
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2 October 2017
The anaphase-promoting complex/cyclosome: APC/C.
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2 October 2017
Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model
1 reference
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PubMed Central
reference URL
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2 October 2017
Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Mitosis: a matter of getting rid of the right protein at the right time
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Anaphase promoting complex or cyclosome?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
On the road to cancer: aneuploidy and the mitotic checkpoint
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The spindle checkpoint: tension versus attachment.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
How do so few control so many?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
retrieved
2 October 2017
Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The dynamic kinetochore-microtubule interface
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Multi-kinase phosphorylation of the APC/C activator Cdh1 revealed by mass spectrometry.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
APC/C and SCF: controlling each other and the cell cycle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Don't skip the G1 phase: how APC/CCdh1 keeps SCFSKP2 in check.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The spindle checkpoint, aneuploidy, and cancer
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PubMed Central
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2 October 2017
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Mitotic regulation of the human anaphase-promoting complex by phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
retrieved
2 October 2017
Regulation of APC-Cdc20 by the spindle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
retrieved
2 October 2017
The destruction box of the cyclin Clb2 binds the anaphase-promoting complex/cyclosome subunit Cdc23.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Attachment and tension in the spindle assembly checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The anaphase-promoting complex: proteolysis in mitosis and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The vertebrate cell kinetochore and its roles during mitosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Budding yeast Cdc20: a target of the spindle checkpoint.
1 reference
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PubMed Central
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2 October 2017
MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Mitosis in vertebrate somatic cells with two spindles: implications for the metaphase/anaphase transition checkpoint and cleavage
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
The spindle assembly checkpoint
1 reference
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PubMed Central
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2 October 2017
Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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2 October 2017
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation
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PubMed Central
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27 July 2018
Mitosis and checkpoints that control progression through mitosis in vertebrate somatic cells
1 reference
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27 July 2018
The APC subunit Doc1 promotes recognition of the substrate destruction box.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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24 September 2018
Aneuploidy and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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24 September 2018
The Mad2 spindle checkpoint protein has two distinct natively folded states
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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24 September 2018
Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
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24 September 2018
The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
retrieved
24 September 2018
Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1947974
retrieved
24 September 2018
Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17650307
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence that the yeast spindle assembly checkpoint has a target other than the anaphase promoting complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17650307
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of Cell Cycle‐Dependent Phosphorylation Sites on the Anaphase‐Promoting Complex/Cyclosome by Mass Spectrometry
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17650307
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/1747-1028-2-23
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Dimensions Publication ID
1045651875
0 references
Fatcat ID
release_kyu23xroz5hvrpsxlhi5prmlzm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/kyu23xroz5hvrpsxlhi5prmlzm
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
1947974
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
PubMed publication ID
17650307
1 reference
stated in
Europe PubMed Central
PMC publication ID
1947974
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17650307%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
ResearchGate publication ID
6189013
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