(Q35943971)

English

Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism

scientific article published on 19 March 2012

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

11 August 2017

Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism (English)

1 reference

Europe PubMed Central

11 August 2017

toll-like receptor

0 references

1 reference

based on heuristic

inferred from title

14

object named as

Barbara B Kahn

1 reference

Europe PubMed Central

11 August 2017

Roger John Davis

12

object named as

Roger J Davis

1 reference

Europe PubMed Central

11 August 2017

author name string

Julie Norseen

1

1 reference

Europe PubMed Central

11 August 2017

Tetsuya Hosooka

2

1 reference

Europe PubMed Central

11 August 2017

Ann Hammarstedt

3

1 reference

Europe PubMed Central

11 August 2017

Mark M Yore

4

1 reference

Europe PubMed Central

11 August 2017

Shashi Kant

5

1 reference

Europe PubMed Central

11 August 2017

Pratik Aryal

6

1 reference

Europe PubMed Central

11 August 2017

Urban A Kiernan

7

1 reference

Europe PubMed Central

11 August 2017

David A Phillips

8

1 reference

Europe PubMed Central

11 August 2017

Hiroshi Maruyama

9

1 reference

Europe PubMed Central

11 August 2017

Bettina J Kraus

10

1 reference

Europe PubMed Central

11 August 2017

Anny Usheva

11

1 reference

Europe PubMed Central

11 August 2017

Ulf Smith

13

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

19 March 2012

1 reference

Europe PubMed Central

11 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

11 August 2017

32

1 reference

Europe PubMed Central

11 August 2017

10

1 reference

Europe PubMed Central

11 August 2017

2010-2019

1 reference

Europe PubMed Central

11 August 2017

Quantitative measurement of full-length and C-terminal proteolyzed RBP4 in serum of normal and insulin-resistant humans using a novel mass spectrometry immunoassay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Emerging roles for retinoids in regeneration and differentiation in normal and disease states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Inflammatory concepts of obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

RBP4: a controversial adipokine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Retinol-binding protein 4 is associated with prediabetes in adults from the general population: the Cooperative Health Research in the Region of Augsburg (KORA) F4 Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Quantitative mass spectrometry evaluation of human retinol binding protein 4 and related variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Retinoic acid: a key player in immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Lipid-induced insulin resistance: unravelling the mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Macrophages, inflammation, and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Regulation and function of NF-kappaB transcription factors in the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Induction of hepatitis by JNK-mediated expression of TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Isoforms of retinol binding protein 4 (RBP4) are increased in chronic diseases of the kidney but not of the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Retinol-binding protein 4, visceral fat, and the metabolic syndrome: effects of weight loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Retinol to retinol-binding protein (RBP) is low in obese adults due to elevated apo-RBP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

An RBP4 promoter polymorphism increases risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Leptin beyond body weight regulation--current concepts concerning its role in immune function and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Adipokines in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

SOCS proteins causing trouble in insulin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

STRA6, a cell-surface receptor for retinol-binding protein: the plot thickens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Vitamin A regulation of gene expression: molecular mechanism of a prototype gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Inflammation, stress, and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

IKK-beta links inflammation to obesity-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Adipose tissue as an endocrine organ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

A central role for JNK in obesity and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

LPS induction of gene expression in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

2 October 2017

PPARs and lipid ligands in inflammation and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

27 July 2018

Retinol-binding protein-4 in women with untreated essential hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

RBP-to-retinol ratio, but not total RBP, is elevated in patients with type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Retinol-binding protein 4 is associated with impaired glucose tolerance but not with whole body or hepatic insulin resistance in Mexican Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Serum retinol-binding protein 4 is not increased in obesity or obesity-associated type 2 diabetes mellitus, but is reduced after relevant reductions in body fat following gastric bypass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Visceral adiposity is associated with serum retinol binding protein-4 levels in healthy women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Elevated retinol-binding protein 4 levels are associated with metabolic syndrome in Chinese people.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Insulin resistance is unrelated to circulating retinol binding protein and protein C inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Effect of weight loss on LDL and HDL kinetics in the metabolic syndrome: associations with changes in plasma retinol-binding protein-4 and adiponectin levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Association of serum retinol-binding protein 4 and visceral adiposity in Chinese subjects with and without type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Analysis of the factors contributing to serum retinol binding protein and transthyretin levels in Japanese adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

24 September 2018

Adipose tissue as an endocrine organ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3347417

14 November 2018

Chemical genetic analysis of the time course of signal transduction by JNK

1 reference

https://pubmed.ncbi.nlm.nih.gov/22431523

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of carotenoid, vitamin A, and alpha-tocopheral levels in human lung tissue and pulmonary macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/22431523

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22431523

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/22431523

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22431523

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinol-binding protein-4 attenuates insulin-induced phosphorylation of IRS1 and ERK1/2 in primary human adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22431523

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.06193-11

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35943971&oldid=1888684691"