(Q35956173)

11 August 2017

1 reference

title

Coordinate regulation of drug metabolism by xenobiotic nuclear receptors: UGTs acting together with CYPs and glucuronide transporters (English)

1 reference

11 August 2017

Karl Walter Bock

1

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11 August 2017

Christoph Köhle

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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11 August 2017

published in

Drug Metabolism Reviews

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11 August 2017

volume

36

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11 August 2017

issue

3-4

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11 August 2017

page(s)

595-615

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Physiological role of the N-terminal processed P4501A1 targeted to mitochondria in erythromycin metabolism and reversal of erythromycin-mediated inhibition of mitochondrial protein synthesis

11 August 2017

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Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin

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Purification of Rat-Liver Microsomal UDP-glucuronyltransferase. Separation of Two Enzyme Forms Inducible by 3-Methylcholanthrene or Phenobarbital

21 January 2018

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Induction of drug-metabolizing enzymes by xenobiotics

21 January 2018

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Regioselectivity of phase II metabolism of luteolin and quercetin by UDP-glucuronosyl transferases.

21 January 2018

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An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone binding.

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Effect of phenobarbital and naphthalene on some of the components of the electron transport system and the hydroxylating activity of house fly microsomes

21 January 2018

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Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats

21 January 2018

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Differential expression and induction of UDP-glucuronosyltransferase isoforms in hepatic and extrahepatic tissues of a fish, Pleuronectes platessa: immunochemical and functional characterization

21 January 2018

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Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms

21 January 2018

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Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

21 January 2018

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Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

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Drug-Responsive and Tissue-Specific Alternative Expression of Multiple First Exons in Rat UDP-Glucuronosyltransferase Family 1 (UGT1) Gene Complex

21 January 2018

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Loss of analgesic effect of morphine due to coadministration of rifampin

21 January 2018

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Induction of UDP-glucuronosyltransferase by the flavonoids chrysin and quercetin in Caco-2 cells

21 January 2018

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Molecular evidence for multiple UDP-glucuronosyltransferase gene familes in fish

21 January 2018

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Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

21 January 2018

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Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

21 January 2018

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Regulation of cyp3a gene transcription by the pregnane x receptor

21 January 2018

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Formation of mono- and diglucuronides and other glycosides of benzo(a)pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex

21 January 2018

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The PAS superfamily: sensors of environmental and developmental signals

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

Effect of rifampicin treatment on hepatic drug metabolism and serum bile acids in patients with primary biliary cirrhosis.

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

Regulation of cytochrome P450 (CYP) genes by nuclear receptors.

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

Genetic diseases of bilirubin metabolism: the inherited unconjugated hyperbilirubinemias

21 January 2018

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The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

21 January 2018

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Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

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Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

21 January 2018

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Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

4-Hydroxylation of estrogens as marker of human mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Benzo[a]pyrenedione/benzo[a]pyrenediol oxidation-reduction couples and the generation of reactive reduced molecular oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Regulation of UDP glucuronosyltransferase genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Transcriptional activation of the UDP-glucuronosyltransferase 1A7 gene in rat liver by aryl hydrocarbon receptor ligands and oltipraz.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Induction of estradiol metabolism by dietary indole-3-carbinol in humans

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-200033455

UDP-glucosyltransferase activity of housefly microsomal fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6

21 January 2018

1 reference

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Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells

21 January 2018

1 reference

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Proposed role of drug-metabolizing enzymes: regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions

21 January 2018

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P450 genes: structure, evolution, and regulation

21 January 2018

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Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK.

21 January 2018

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UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

[Activation of detoxication in liver microsome during addiction].

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Isolation of the alkane inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Induction of cytochrome P4501A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Orphan nuclear receptors: the exotics of xenobiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Functional role of estrogen metabolism in target cells: review and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

HNF4: A central regulator of hepatocyte differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: effects of phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033455

21 January 2018

Identifiers

DOI

10.1081/DMR-200033455

1 reference

11 August 2017

1 reference