(Q35959371)

11 August 2017

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title

Centrosome amplification and the origin of chromosomal instability in breast cancer (English)

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11 August 2017

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3

Wilma L Lingle

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11 August 2017

1

Jeffrey L Salisbury

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11 August 2017

Antonino B D'Assoro

2

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11 August 2017

1 July 2004

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Journal of Mammary Gland Biology and Neoplasia

11 August 2017

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11 August 2017

9

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11 August 2017

3

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11 August 2017

275-283

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https://scigraph.springernature.com/pub.10.1023/b:jomg.0000048774.27697.30

11 August 2017

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cites work

Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression

1 reference

12 December 2020

Genotoxic stress leads to centrosome amplification in breast cancer cell lines that have an inactive G1/S cell cycle checkpoint

1 reference

12 December 2020

Motile organelles: the importance of specific tubulin isoforms

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12 December 2020

Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness

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12 December 2020

Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.

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12 December 2020

Roles of BRCA1 and its interacting proteins

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12 December 2020

Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999.

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12 December 2020

Microtubule nucleating capacity of centrosomes in tissue sections

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12 December 2020

Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53

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12 December 2020

Centrosome composition and microtubule anchoring mechanisms

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12 December 2020

De novo formation of centrosomes in vertebrate cells arrested during S phase

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12 December 2020

Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers

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12 December 2020

Direct regulation of the centrosome duplication cycle by the p53-p21Waf1/Cip1 pathway

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12 December 2020

Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs

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12 December 2020

Managing the centrosome numbers game: from chaos to stability in cancer cell division

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12 December 2020

Sensitivity of the origin decision point to specific inhibitors of cellular signaling and metabolism

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12 December 2020

Centrosome abnormalities in pancreatic ductal carcinoma.

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12 December 2020

The role of nucleophosmin in centrosome duplication

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12 December 2020

Anaphase onset and dephosphorylation of mitotic phosphoproteins occur concomitantly

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12 December 2020

Centrosomes. Organizing cytoplasmic events.

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12 December 2020

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

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12 December 2020

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

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12 December 2020

GADD45 induction of a G2/M cell cycle checkpoint

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12 December 2020

Centrosome-dependent exit of cytokinesis in animal cells

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12 December 2020

Centrosome and spindle pole body dynamics. Review and abstracts of the EMBO/EMBL Conference on Centrosomes and Spindle Pole Bodies, Heidelberg, September 13-17, 2002

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12 December 2020

Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication

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12 December 2020

Centrosome hyperamplification in head and neck squamous cell carcinoma: a potential phenotypic marker of tumor aggressiveness

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12 December 2020

p53 abnormality and chromosomal instability in the same breast tumor cells

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12 December 2020

Centrosomes: Sfi1p and centrin unravel a structural riddle

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12 December 2020

The chromosome cycle and the centrosome cycle in the mitotic cycle

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12 December 2020

Mutant p53 and genomic instability in a transgenic mouse model of breast cancer

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12 December 2020

Centrosomes as command centres for cellular control

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12 December 2020

Prediction of node-negative breast cancer outcome by histologic grading and S-phase analysis by flow cytometry: an Eastern Cooperative Oncology Group Study (2192).

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12 December 2020

Nuclear redistribution of BRCA1 during viral infection.

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12 December 2020

Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes

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12 December 2020

Pericentrin anchors protein kinase A at the centrosome through a newly identified RII-binding domain

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12 December 2020

WAF1, a potential mediator of p53 tumor suppression

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12 December 2020

Cyclin B is associated with centrosomes in Drosophila mitotic cells

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12 December 2020

Monoclonal antibody against the centrosome

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12 December 2020

The coordination of centrosome reproduction with nuclear events during the cell cycle

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12 December 2020

Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts.

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12 December 2020

Centrin is a component of the periocentriola lattice

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12 December 2020

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

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12 December 2020

Genetic instabilities in human cancers

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12 December 2020

SAS-4 is a C. elegans centriolar protein that controls centrosome size

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12 December 2020

Cytoplasmic accumulation of cyclin B1 in human cells: association with a detergent-resistant compartment and with the centrosome

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12 December 2020

Molecular cytogenetics of primary breast cancer by CGH

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12 December 2020

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

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12 December 2020

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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12 December 2020

Proteomic characterization of the human centrosome by protein correlation profiling

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12 December 2020

Abnormal centrosome amplification in the absence of p53.

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12 December 2020

Cell cycle-dependent phosphorylation of centrosomes: localization of phosphopeptide specific antibodies to the centrosome

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12 December 2020

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

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12 December 2020

Detection of TP53 mutation, loss of heterozygosity and DNA content in fine-needle aspirates of breast carcinoma

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12 December 2020

Beyond self-assembly: from microtubules to morphogenesis

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12 December 2020

Centrosome size is controlled by centriolar SAS-4.

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12 December 2020

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells

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12 December 2020

BRCA1 is associated with the centrosome during mitosis.

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12 December 2020

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

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12 December 2020

A high-affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II in the centrosome of human cells

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12 December 2020

Difference in the centrosome duplication regulatory activity among p53 'hot spot' mutants: potential role of Ser 315 phosphorylation-dependent centrosome binding of p53.

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12 December 2020

Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells

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12 December 2020

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

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12 December 2020

Numerical aberrations of chromosome 17 in interphase cell nuclei of breast carcinoma cells: lack of correlation with abnormal expression of p53, neu and nm23 protein

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12 December 2020

Analysis of chromosome aneuploidy in breast carcinoma progression by using fluorescence in situ hybridization

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12 December 2020

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

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12 December 2020

SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle.

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12 December 2020

p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells

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12 December 2020

Genetic instability in colorectal cancers

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12 December 2020

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

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12 December 2020

Genomic instability in Gadd45a-deficient mice

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12 December 2020

Centrosome defects and genetic instability in malignant tumors

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12 December 2020

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

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12 December 2020

Genomic convergence and suppression of centrosome hyperamplification in primary p53-/- cells in prolonged culture

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12 December 2020

The pericentriolar lattice of PtK2 cells exhibits temperature and calcium-modulated behavior.

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12 December 2020

Kinetics and regulation of de novo centriole assembly. Implications for the mechanism of centriole duplication.

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12 December 2020

No centriole, no centrosome

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12 December 2020

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

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12 December 2020

Cyclin-dependent kinase control of centrosome duplication

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12 December 2020

Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification

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12 December 2020

Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle

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12 December 2020

Mechanisms of tumor metastasis: cell biological aspects and clinical implications

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12 December 2020

Centrosome amplification and the development of cancer

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12 December 2020

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

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12 December 2020

Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

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12 December 2020

The tubulin fraternity: alpha to eta

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12 December 2020

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

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12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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12 December 2020

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

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12 December 2020

Centrosomes: coiled-coils organize the cell center

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12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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12 December 2020

Spindle pole body duplication: a model for centrosome duplication?

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12 December 2020

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

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12 December 2020

Regulating centrosomes by protein phosphorylation.

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12 December 2020

Centrosome amplification drives chromosomal instability in breast tumor development

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12 December 2020

Molecular characterisation of ninein, a new coiled-coil protein of the centrosome

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12 December 2020

Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression

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12 December 2020

Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication

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12 December 2020

10.1023/B:JOMG.0000048774.27697.30

Identifiers

DOI

1 reference

PubMed ID

15557800

Dimensions Publication ID

11 August 2017

0 references

1 reference

PubMed ID

15557800