(Q35964712)

11 August 2017

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title

The therapeutic potential of agents targeting the type I insulin-like growth factor receptor (English)

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11 August 2017

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Hua Zhang

1

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11 August 2017

Douglas Yee

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

1 December 2004

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Expert Opinion on Investigational Drugs

11 August 2017

published in

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11 August 2017

volume

13

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11 August 2017

issue

12

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11 August 2017

page(s)

1569-1577

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The EGF receptor family as targets for cancer therapy

11 August 2017

cites work

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

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Structure and function of the insulin-like growth factor I receptor

21 January 2018

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Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man.

21 January 2018

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In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A.

21 January 2018

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Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

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Tyrosine kinase signalling in breast cancer: insulin-like growth factors and their receptors in breast cancer.

21 January 2018

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The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor

21 January 2018

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Insulin-like growth factor binding proteins (IGFBPs) in breast cancer

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Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor

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The insulin-like growth factor system and cancer

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The insulin-like growth factor I receptor gene is the target for the 15q26 amplicon in breast cancer.

21 January 2018

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The constitutively active mutant Galpha13 transforms mouse fibroblast cells deficient in insulin-like growth factor-I receptor

21 January 2018

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The IGF‐1 receptor in cancer biology

21 January 2018

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Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells

21 January 2018

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Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells

21 January 2018

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Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines

21 January 2018

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A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells.

21 January 2018

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Overexpression of Insulin Receptors in Fibroblast and Ovary Cells Induces a Ligand-Mediated Transformed Phenotype

21 January 2018

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Inhibition of rat C6 glioblastoma tumor growth by expression of insulin-like growth factor I receptor antisense mRNA.

21 January 2018

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Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone recepto

21 January 2018

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Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors

21 January 2018

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

21 January 2018

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Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics

21 January 2018

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Substrate competitive inhibitors of IGF-1 receptor kinase

21 January 2018

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Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice

21 January 2018

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Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth

21 January 2018

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Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells.

21 January 2018

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Development of resistance to insulin-like growth factor binding protein-3 in transfected T47D breast cancer cells

21 January 2018

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Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

21 January 2018

1 reference

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Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells.

21 January 2018

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Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence

21 January 2018

1 reference

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Insulin-like growth factors and neoplasia.

21 January 2018

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Antitumor activity of the growth hormone receptor antagonist pegvisomant against human meningiomas in nude mice

21 January 2018

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Serial analysis of gene expression

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.13.12.1569

10.1517/13543784.13.12.1569

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference