(Q35966272)

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A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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endoplasmic reticulum

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0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Annette Kopp-Schneider

object named as

A Kopp-Schneider

4

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author name string

J Noack

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

J Choi

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

K Richter

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

A Régnier-Vigouroux

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

25 September 2014

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Cell Death and Disease

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

e1425

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4540206/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The chemical basis of serine palmitoyltransferase inhibition by myriocin

1 reference

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Sphingosine kinase activity is not required for tumor cell viability

1 reference

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2 October 2017

Roles, regulation and inhibitors of sphingosine kinase 2.

1 reference

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2 October 2017

Sphingosine kinase 1 in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy

1 reference

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2 October 2017

Glutathione peroxidase 1 activity dictates the sensitivity of glioblastoma cells to oxidative stress

1 reference

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2 October 2017

The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death

1 reference

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2 October 2017

Dihydroceramide desaturase and dihydrosphingolipids: debutant players in the sphingolipid arena

1 reference

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2 October 2017

Sphingosine-1-phosphate signaling and its role in disease

1 reference

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2 October 2017

Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules

1 reference

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2 October 2017

Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide.

1 reference

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2 October 2017

Sphingolipid rheostat alterations related to transformation can be exploited for specific induction of lysosomal cell death in murine and human glioma

1 reference

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2 October 2017

Sphingosine 1-phosphate and cancer

1 reference

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2 October 2017

Dihydroceramide desaturase activity is modulated by oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Temozolomide in malignant gliomas: current use and future targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

1 reference

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2 October 2017

New (alternative) temozolomide regimens for the treatment of glioma

1 reference

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2 October 2017

Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response.

1 reference

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2 October 2017

Sphingolipid signaling pathways as potential therapeutic targets in gliomas

1 reference

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2 October 2017

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

1 reference

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Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Discovery and evaluation of inhibitors of human sphingosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Sphingosine 1-phosphate, a diffusible calcium influx factor mediating store-operated calcium entry.

1 reference

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Sphingosine-1-phosphate: an enigmatic signalling lipid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540206

2 October 2017

Serine palmitoyltransferase: role in apoptotic de novo ceramide synthesis and other stress responses

1 reference

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Radiation induced CNS toxicity--molecular and cellular mechanisms

1 reference

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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

1 reference

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2 October 2017

Different angiogenic phenotypes in primary and secondary glioblastomas

1 reference

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27 July 2018

Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids

1 reference

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27 July 2018

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.

1 reference

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24 September 2018

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

1 reference

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Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis

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Mechanism of selenium-glutathione peroxidase and its inhibition by mercaptocarboxylic acids and other mercaptans.

1 reference

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Induction of endoplasmic reticulum stress by the pro-apoptotic retinoid N-(4-hydroxyphenyl)retinamide via a reactive oxygen species-dependent mechanism in human head and neck cancer cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/CDDIS.2014.384

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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