(Q35968077)

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Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation

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Europe PubMed Central

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22 February 2020

Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation (English)

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22 February 2020

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22 February 2020

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22 February 2020

Manoj K Jaiswal

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22 February 2020

Daniela Cornacchia

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22 February 2020

Peter A. Goldstein

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22 February 2020

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22 February 2020

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Viviane Tabar

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22 February 2020

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Elizabeth L Calder

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22 February 2020

Julius A Steinbeck

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22 February 2020

Edmund Tu

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22 February 2020

Shui-Wang Ying

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22 February 2020

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1 August 2015

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22 February 2020

Journal of Neuroscience

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22 February 2020

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22 February 2020

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22 February 2020

11462-11481

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22 February 2020

High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1.

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2 October 2017

How to make spinal motor neurons

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2 October 2017

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1 reference

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2 October 2017

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.

1 reference

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2 October 2017

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1 reference

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2 October 2017

Accelerated high-yield generation of limb-innervating motor neurons from human stem cells

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2 October 2017

Maturation of spinal motor neurons derived from human embryonic stem cells

1 reference

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2 October 2017

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1 reference

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2 October 2017

Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus

1 reference

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2 October 2017

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

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Conversion of mouse and human fibroblasts into functional spinal motor neurons

1 reference

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2 October 2017

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state

1 reference

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2 October 2017

A functionally characterized test set of human induced pluripotent stem cells

1 reference

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2 October 2017

Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation

1 reference

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2 October 2017

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

1 reference

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2 October 2017

Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540792

2 October 2017

Differentiation of spinal motor neurons from pluripotent human stem cells

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2 October 2017

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

1 reference

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2 October 2017

BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage.

1 reference

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2 October 2017

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

1 reference

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2 October 2017

Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

1 reference

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2 October 2017

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

1 reference

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2 October 2017

Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540792

2 October 2017

Functional properties of motoneurons derived from mouse embryonic stem cells.

1 reference

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2 October 2017

Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

1 reference

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2 October 2017

Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord

1 reference

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2 October 2017

Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats

1 reference

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2 October 2017

All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3

1 reference

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2 October 2017

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

1 reference

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2 October 2017

A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

1 reference

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2 October 2017

Directed differentiation of embryonic stem cells into motor neurons

1 reference

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2 October 2017

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

1 reference

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2 October 2017

A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube

1 reference

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2 October 2017

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

1 reference

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2 October 2017

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1 reference

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2 October 2017

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

1 reference

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2 October 2017

Evidence that Shh cooperates with a retinoic acid inducible co-factor to establish ZPA-like activity.

1 reference

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2 October 2017

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1 reference

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2 October 2017

Postaxial polydactyly in forelimbs of CRABP-II mutant mice

1 reference

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2 October 2017

Morphogenesis of retinoic acid-induced postaxial polydactyly in mice

1 reference

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2 October 2017

A novel Gli3 enhancer controls the Gli3 spatiotemporal expression pattern through a TALE homeodomain protein binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540792

11 July 2018

Efficient derivation of functional floor plate tissue from human embryonic stem cells

1 reference

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11 July 2018

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1 reference

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11 July 2018

Neurons derived in vitro from ES cells express homeoproteins characteristic of motoneurons and interneurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4540792

11 July 2018

Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals.

1 reference

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24 September 2018

A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud.

1 reference

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24 September 2018

Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.

1 reference

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24 September 2018

Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons.

1 reference

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24 September 2018

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1 reference

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24 September 2018

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1 reference

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24 September 2018

Specification of motoneurons from human embryonic stem cells.

1 reference

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24 September 2018

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1 reference

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24 September 2018

Motor neuron columnar fate imposed by sequential phases of Hox-c activity.

1 reference

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24 September 2018

Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.

1 reference

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24 September 2018

Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/26290227

12 December 2020

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10.1523/JNEUROSCI.3046-14.2015

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22 February 2020

1 reference

Europe PubMed Central

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22 February 2020

1 reference

Europe PubMed Central

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22 February 2020

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