(Q35973936)

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Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

Europe PubMed Central

Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

author name string

Steven L Carroll

1

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Mark S Stonecypher

2

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

publication date

1 November 2004

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Europe PubMed Central

PubMed publication ID

11 August 2017

Journal of Neuropathology & Experimental Neurology

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Europe PubMed Central

PubMed publication ID

11 August 2017

63

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Europe PubMed Central

PubMed publication ID

11 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1115-1123

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2.

1 reference

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The neurofibromatoses: when less is more

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Plexiform neurofibromas in NF1: toward biologic-based therapy

1 reference

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Neurofibroma and schwannoma

1 reference

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Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases

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Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis

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Angiogenic and invasive properties of neurofibroma Schwann cells

1 reference

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Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression

1 reference

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Tumorigenic properties of neurofibromin-deficient neurofibroma Schwann cells

1 reference

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Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells

1 reference

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Neurofibromin, a tumor suppressor in the nervous system

1 reference

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Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

1 reference

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NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors

1 reference

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Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells

1 reference

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

1 reference

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1 reference

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Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

1 reference

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A role for Pak protein kinases in Schwann cell transformation

1 reference

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Signal transduction by the JNK group of MAP kinases

1 reference

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Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1

1 reference

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p21-activated kinase links Rac/Cdc42 signaling to merlin

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Correlation between clinicopathological features and karyotype in spindle cell sarcomas. A report of 130 cases from the CHAMP study group

1 reference

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Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

1 reference

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R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells

1 reference

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Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

1 reference

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21 January 2018

p53, the cellular gatekeeper for growth and division

1 reference

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21 January 2018

Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

1 reference

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21 January 2018

Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant peripheral nerve sheath tumours.

1 reference

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Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas

1 reference

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Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation

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21 January 2018

Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

1 reference

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21 January 2018

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

1 reference

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21 January 2018

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

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Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects

1 reference

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Mouse models of tumor development in neurofibromatosis type 1

1 reference

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Neurofibromas in NF1: Schwann cell origin and role of tumor environment

1 reference

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Mouse tumor model for neurofibromatosis type 1

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Comparative genomic hybridization analysis of human sarcomas: I. Occurrence of genomic imbalances and identification of a novel major amplicon at 1q21-q22 in soft tissue sarcomas

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Cytogenetic characterization of six malignant peripheral nerve sheath tumors: comparison of karyotyping and comparative genomic hybridization.

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Evidence for involvement of a tumor suppressor gene on 1p in malignant peripheral nerve sheath tumors

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Notch and Schwann cell transformation

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21 January 2018

Identifiers

10.1093/JNEN/63.11.1115

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

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