(Q35982455)

11 August 2017

Bioreductive drugs and the selective induction of tumour hypoxia (English)

1 reference

11 August 2017

2

I J Stratford

1 reference

11 August 2017

J C Bremner

1

1 reference

11 August 2017

J Bowler

series ordinal

3

1 reference

11 August 2017

G E Adams

series ordinal

4

1 reference

11 August 2017

language of work or name

English

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publication date

1 May 1990

1 reference

British Journal of Cancer

11 August 2017

1 reference

11 August 2017

61

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11 August 2017

5

1 reference

11 August 2017

717-721

1 reference

https://scigraph.springernature.com/pub.10.1038/bjc.1990.161

11 August 2017

0 references

cites work

The histological structure of some human lung cancers and the possible implications for radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Response of Chinese hamster ovary cells to anticancer drugs under aerobic and hypoxic conditions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Chemotherapy of human breast-carcinoma xenografts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

The development of hypoxic tumor cell cytotoxic agents

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Radiosensitization by Misonidazole (Ro 07-0582) The Importance of Timing and Tumor Concentration of Sensitizer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

A new mouse tumor model system (RIF-1) for comparison of end-point studies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Selective chemotherapy of noncycling cells in an in vitro tumor model

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Pharmacokinetics and metabolism of the mixed-function hypoxic cell sensitizer prototype RSU 1069 in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Induction of tumour hypoxia by a vasoactive agent. A combined NMR and radiobiological study

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1971619

The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: evidence for therapeutic gain

24 September 2018

1 reference

12 December 2020

Acute hypoxia in tumors: implications for modifiers of radiation effects

1 reference

12 December 2020

Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR 4233

1 reference

12 December 2020

Isolation of Chinese hamster ovary cell mutants deficient in excision repair and mitomycin C bioactivation

1 reference

12 December 2020

Induction of tumour hypoxia post-irradiation: a method for increasing the sensitizing efficiency of misonidazole and RSU 1069 in vivo

1 reference

12 December 2020

Molecular enzymology of the reductive bioactivation of hypoxic cell cytotoxins

1 reference

12 December 2020

High uptake of RSU 1069 and its analogues melanotic melanomas

1 reference

12 December 2020

RESPONSE OF SPONTANEOUS MAMMARY CARCINOMA OF THE C3H MOUSE TO X IRRADIATION GIVEN UNDER CONDITIONS OF LOCAL TISSUE ANOXIA

1 reference

12 December 2020

The therapeutic response of three human tumor lines maintained in immune-suppressed mice

1 reference

12 December 2020

Modification of guanine derivatives by reduced 2-nitroimidazoles

1 reference

12 December 2020

Vascular occlusion and tumour cell death

1 reference

12 December 2020

Activity of mitomycin C for aerobic and hypoxic cells in vitro and in vivo

1 reference

12 December 2020

Studies on the toxicity of RSU-1069

1 reference

12 December 2020

Induction of DNA crosslinks in vitro upon reduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1990.161

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

2110814

1 reference