(Q35987505)

11 August 2017

Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors (English)

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11 August 2017

Alexander W Sorum

2

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Jordan L Meier

object named as

Jordan L Meier

5

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Marc C Nicklaus

object named as

Marc C Nicklaus

4

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author name string

David C Montgomery

1

1 reference

11 August 2017

Laura Guasch

3

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11 August 2017

15 July 2015

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11 August 2017

Chemistry and Biology

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11 August 2017

22

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11 August 2017

8

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11 August 2017

1030-1039

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describes a project that uses

11 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4546520/fullTextXML

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Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation

2 October 2017

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Chemoproteomic profiling of lysine acetyltransferases highlights an expanded landscape of catalytic acetylation

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

2 October 2017

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Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

2 October 2017

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The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation

2 October 2017

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Protein lysine acylation and cysteine succination by intermediates of energy metabolism

2 October 2017

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The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake

2 October 2017

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Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.

2 October 2017

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Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: a mechanism integrating glycolytic flux with lipid metabolism

2 October 2017

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KAT(ching) metabolism by the tail: insight into the links between lysine acetyltransferases and metabolism

2 October 2017

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Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

2 October 2017

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An electrophoretic mobility shift assay for the identification and kinetic analysis of acetyl transferase inhibitors

2 October 2017

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Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

2 October 2017

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ATP-citrate lyase links cellular metabolism to histone acetylation

2 October 2017

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Global levels of histone modifications predict prognosis in different cancers

2 October 2017

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Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome

2 October 2017

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Crystal structure of a binary complex between human GCN5 histone acetyltransferase domain and acetyl coenzyme A

2 October 2017

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Lysine propionylation and butyrylation are novel post-translational modifications in histones

2 October 2017

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Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

2 October 2017

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Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance

2 October 2017

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Liver fatty acid-binding protein colocalizes with peroxisome proliferator activated receptor alpha and enhances ligand distribution to nuclei of living cells

2 October 2017

1 reference

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Selective HAT inhibitors as mechanistic tools for protein acetylation

2 October 2017

1 reference

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Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

2 October 2017

1 reference

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

2 October 2017

1 reference

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Histone acetyltransferases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546520

HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

2 October 2017

1 reference

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Structure and ligand of a histone acetyltransferase bromodomain

2 October 2017

1 reference

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Large-scale synthesis of coenzyme A esters

2 October 2017

1 reference

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Labeling lysine acetyltransferase substrates with engineered enzymes and functionalized cofactor surrogates.

27 July 2018

1 reference

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The human histone acetyltransferase P/CAF is a promiscuous histone propionyltransferase

24 September 2018

1 reference

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Global histone modification patterns predict risk of prostate cancer recurrence

24 September 2018

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Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546520

Transcriptional coactivator protein p300. Kinetic characterization of its histone acetyltransferase activity

24 September 2018

1 reference

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Extraction of tissue long-chain acyl-CoA esters and measurement by reverse-phase high-performance liquid chromatography.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546520

Physical properties of fatty acyl-CoA. Critical micelle concentrations and micellar size and shape.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546520

Ligand selectivity of the peroxisome proliferator-activated receptor alpha

24 September 2018

1 reference

12 December 2020

Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α

1 reference

12 December 2020

Long-chain fatty Acyl-CoA synthetase enzymatic activity in rat liver cell nuclei

1 reference

12 December 2020

Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells

1 reference

12 December 2020

A continuous, nonradioactive assay for histone acetyltransferases

1 reference

12 December 2020

Kinetic mechanism of human histone acetyltransferase P/CAF

1 reference

12 December 2020

A Coenzyme A analogue, Desulpho-CoA; Preparation and effects on various enzymes

1 reference

12 December 2020

Specific inhibition of glucokinase by long chain acyl coenzymes A below the critical micelle concentration

1 reference

12 December 2020

Carnitine acyltransferases and acyl-CoA hydrolases in human and rat liver

1 reference

12 December 2020

Fatty acyl-CoAs are potent inhibitors of the nuclear thyroid hormone receptor in vitro

1 reference

12 December 2020

Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain f

1 reference

12 December 2020

Kinetic mechanism of the histone acetyltransferase GCN5 from yeast

1 reference

12 December 2020

10.1016/J.CHEMBIOL.2015.06.015

Identifiers

DOI

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

26190825

1 reference