(Q36000073)

11 August 2017

Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice (English)

1 reference

11 August 2017

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747754%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Timothy L. Domeier

5

1 reference

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5 June 2020

author name string

Brian Bostick

1

1 reference

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5 June 2020

Javad Habibi

2

1 reference

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5 June 2020

Guanghong Jia

4

1 reference

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5 June 2020

Michelle D Lambert

6

1 reference

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5 June 2020

Annayya R Aroor

7

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5 June 2020

Ravi Nistala

8

1 reference

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5 June 2020

Shawn B Bender

9

1 reference

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5 June 2020

Mona Garro

10

1 reference

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5 June 2020

Melvin R Hayden

11

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5 June 2020

Lixin Ma

12

1 reference

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5 June 2020

Camila Manrique

13

1 reference

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5 June 2020

James R Sowers

14

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5 June 2020

publication date

6 March 2015

1 reference

American Journal of Physiology Heart and Circulatory Physiology

11 August 2017

1 reference

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5 June 2020

volume

308

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5 June 2020

issue

9

1 reference

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5 June 2020

page(s)

H1126-35

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describes a project that uses

5 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4551127/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Uric acid promotes left ventricular diastolic dysfunction in mice fed a Western diet.

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2 October 2017

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Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies

2 October 2017

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Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a mouse model of Western diet induced obesity

2 October 2017

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2 October 2017

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2 October 2017

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Obesity and insulin resistance induce early development of diastolic dysfunction in young female mice fed a Western diet

2 October 2017

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A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation

2 October 2017

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Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats

2 October 2017

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Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

2 October 2017

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Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease?

2 October 2017

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2 October 2017

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2 October 2017

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mTOR signalling: the molecular interface connecting metabolic stress, aging and cardiovascular diseases

2 October 2017

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Diabetic cardiomyopathy: bench to bedside

2 October 2017

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Insulin resistance and heart failure: molecular mechanisms

2 October 2017

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Regulation of Overnutrition-Induced Cardiac Inflammatory Mechanisms

2 October 2017

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Molecular and cellular basis for diastolic dysfunction

2 October 2017

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Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets

2 October 2017

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Arterial stiffness and wave reflection: sex differences and relationship with left ventricular diastolic function

2 October 2017

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An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile

2 October 2017

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Diabetes, oxidative stress, molecular mechanism, and cardiovascular disease--an overview.

2 October 2017

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The Impact of Overnutrition on Insulin Metabolic Signaling in the Heart and the Kidney

2 October 2017

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Role of differential signaling pathways and oxidative stress in diabetic cardiomyopathy

2 October 2017

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Immunity as a link between obesity and insulin resistance

2 October 2017

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Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation

2 October 2017

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Estrogen signaling and cardiovascular disease

2 October 2017

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Sex and type 2 diabetes: obesity-independent effects on left ventricular substrate metabolism and relaxation in humans

2 October 2017

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Mineralocorticoid receptors in vascular function and disease

2 October 2017

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Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways.

2 October 2017

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2 October 2017

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2 October 2017

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Comparative analysis of telmisartan and olmesartan on cardiac function in the transgenic (mRen2)27 rat

2 October 2017

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Oxidative stress regulates left ventricular PDE5 expression in the failing heart

2 October 2017

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2 October 2017

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2 October 2017

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Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice

2 October 2017

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2 October 2017

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2 October 2017

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Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines

2 October 2017

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Aldosterone and vascular inflammation

2 October 2017

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Targeting mammalian target of rapamycin (mTOR) for health and diseases.

2 October 2017

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

2 October 2017

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Aldosterone, mineralocorticoid receptors and vascular inflammation

2 October 2017

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Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

2 October 2017

1 reference

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Aldosterone-induced inflammation in the rat heart : role of oxidative stress

2 October 2017

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Mineralocorticoids and cardiac fibrosis: the decade in review

2 October 2017

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Intracellular distribution of peroxynitrite during doxorubicin cardiomyopathy: evidence for selective impairment of myofibrillar creatine kinase

2 October 2017

1 reference

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Impact of diabetes on coronary artery disease in women and men: a meta-analysis of prospective studies

2 October 2017

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Patterns of body fat deposition in youth and their relation to left ventricular markers of adverse cardiovascular prognosis

2 October 2017

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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

2 October 2017

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Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women

2 October 2017

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The impact of gender and general risk factors on the occurrence of atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus

2 October 2017

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Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

2 October 2017

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Age- and gender-related ventricular-vascular stiffening: a community-based study.

2 October 2017

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Trends in lifetime risk and years of life lost due to diabetes in the USA, 1985-2011: a modelling study

11 July 2018

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Fibrosis and cardiac function in obesity: a randomised controlled trial of aldosterone blockade.

23 September 2018

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A randomized study of the beneficial effects of aldosterone antagonism on LV function, structure, and fibrosis markers in metabolic syndrome.

23 September 2018

1 reference

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Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4551127

Different impact of the metabolic syndrome on left ventricular structure and function in hypertensive men and women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4551127

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4551127

Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4551127

Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro

23 September 2018

1 reference

12 December 2020

Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging

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12 December 2020

Prevalence of left ventricular diastolic dysfunction in obese persons with and without diabetes mellitus

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12 December 2020

Clinical application of pulsed Doppler tissue imaging for assessing abnormal left ventricular relaxation

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12 December 2020

Oxidative stress and heart failure

1 reference

12 December 2020

Mineralocorticoid Receptor Antagonist Reduces Renal Injury in Rodent Models of Types 1 and 2 Diabetes Mellitus

1 reference

12 December 2020

Diabetes mellitus, a predictor of morbidity and mortality in the Studies of Left Ventricular Dysfunction (SOLVD) Trials and Registry

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12 December 2020

Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle

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12 December 2020

10.1152/AJPHEART.00898.2014

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747754%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747754%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25747754%20AND%20SRC:MED&resulttype=core&format=json