(Q36002013)

11 August 2017

Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion (English)

1 reference

11 August 2017

Miguel Ganuza

1

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Gonzalo Gómez-López

object named as

Gonzalo Gómez

4

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David G. Pisano

object named as

David Pisano

7

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Maria A Blasco

object named as

María A Blasco

6

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author name string

Cristina Sáiz-Ladera

2

1 reference

11 August 2017

Marta Cañamero

3

1 reference

11 August 2017

Ralph Schneider

5

1 reference

11 August 2017

Jesús M Paramio

8

1 reference

11 August 2017

David Santamaría

9

1 reference

11 August 2017

Mariano Barbacid

10

1 reference

11 August 2017

language of work or name

English

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publication date

13 April 2012

1 reference

11 August 2017

1 reference

11 August 2017

31

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11 August 2017

11

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11 August 2017

2498-2510

1 reference

describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3365431/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3365431

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The role of telomeres and telomerase in stem cell aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

The longest telomeres: a general signature of adult stem cell compartments

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

High-throughput telomere length quantification by FISH and its application to human population studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Secrets of a double agent: CDK7 in cell-cycle control and transcription

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Mammalian cyclin-dependent kinases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

2 October 2017

1 reference

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CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Genomewide production of multipurpose alleles for the functional analysis of the mouse genome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

E2F target genes: unraveling the biology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Cdk2 knockout mice are viable

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Human housekeeping genes are compact

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

Cdk1 is sufficient to drive the mammalian cell cycle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

The role of Cdk7 in CAK function, a retro-retrospective

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365431

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

27 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Conditional ablation of the Mat1 subunit of TFIIH in Schwann cells provides evidence that Mat1 is not required for general transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Stem cells and the rate of living

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Use of within-array replicate spots for assessing differential expression in microarray experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Delayed ageing through damage protection by the Arf/p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.94

Pathology of aging B6;129 mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22505032

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2012.94

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22505032

1 reference