(Q36004582)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Down syndrome and genetics - a case of linked histories (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

David Patterson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 February 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Nature Reviews Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

137-147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15640809%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrg1525

7 January 2020

exact match

0 references

1 reference

Early senile dementia in mongoloid idiocy.

21 January 2018

1 reference

On the diagnostic term “Down's disease”

21 January 2018

1 reference

Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in tissue culture

21 January 2018

1 reference

Down syndrome congenital heart disease: a narrowed region and a candidate gene

21 January 2018

1 reference

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

Pattern of malignant disorders in individuals with Down's syndrome.

21 January 2018

1 reference

The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21

21 January 2018

1 reference

Patterns of Meiotic Recombination on the Long Arm of Human Chromosome 21

21 January 2018

1 reference

Down syndrome: genetic recombination and the origin of the extra chromosome 21.

21 January 2018

1 reference

Integration of cytogenetic landmarks into the draft sequence of the human genome

21 January 2018

1 reference

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

21 January 2018

1 reference

Continuum of overlapping clones spanning the entire human chromosome 21q.

21 January 2018

1 reference

The DNA sequence of human chromosome 21

21 January 2018

1 reference

A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q

21 January 2018

1 reference

Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22

21 January 2018

1 reference

Initial sequencing and comparative analysis of the mouse genome

21 January 2018

1 reference

Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions

21 January 2018

1 reference

Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21.

21 January 2018

1 reference

Global up-regulation of chromosome 21 gene expression in the developing down syndrome brain

21 January 2018

1 reference

Human chromosome 21 gene expression atlas in the mouse.

21 January 2018

1 reference

Large-scale transcriptional activity in chromosomes 21 and 22

21 January 2018

1 reference

DNA sequence and comparative analysis of chimpanzee chromosome 22.

21 January 2018

1 reference

Divergence of the genes on human chromosome 21 between human and other hominoids and variation of substitution rates among transcription units

21 January 2018

1 reference

Autosomal aneuploidy in mice: generation and developmental consequences

21 January 2018

1 reference

A mouse model for Down syndrome exhibits learning and behaviour deficits.

21 January 2018

1 reference

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

21 January 2018

1 reference

Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

21 January 2018

1 reference

Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.

21 January 2018

1 reference

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

21 January 2018

1 reference

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

21 January 2018

1 reference

Global disruption of the cerebellar transcriptome in a Down syndrome mouse model.

21 January 2018

1 reference

Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome

21 January 2018

1 reference

Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

21 January 2018

1 reference

Reversible impairment of long-term potentiation in transgenic Cu/Zn-SOD mice.

21 January 2018

1 reference

Functional and morphological alterations in compound transgenic mice overexpressing Cu/Zn superoxide dismutase and amyloid precursor protein [correction].

21 January 2018

1 reference

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

21 January 2018

1 reference

Altered brain glucose metabolism in transgenic-PFKL mice with elevated L-phosphofructokinase: in vivo NMR studies.

21 January 2018

1 reference

Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks

21 January 2018

1 reference

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis.

21 January 2018

1 reference

The neuropsychology of Down syndrome: evidence for hippocampal dysfunction

21 January 2018

1 reference

Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study.

21 January 2018

1 reference

Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21.

21 January 2018

1 reference

Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.

21 January 2018

1 reference

A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

21 January 2018

1 reference

Chorionic villus sampling for first-trimester prenatal diagnosis: Northwestern University program

21 January 2018

1 reference

Screening for Down's syndrome in early and late first and second trimester using six maternal serum markers.

21 January 2018

1 reference

Homocysteine metabolism in children with Down syndrome: in vitro modulation

21 January 2018

1 reference

Frequency of Down's syndrome and neural-tube defects in the same family

21 January 2018

1 reference

To err (meiotically) is human: the genesis of human aneuploidy

21 January 2018

1 reference

Grandmaternal age at birth of parents of children with trisomy 21

21 January 2018

1 reference

An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde".

21 January 2018

1 reference

Beiträge zur Kenntniss der Zelle und Ihrer Lebenserscheinungen

31 March 2020

1 reference

THE Y-CHROMOSOME IN MAMMALS.

31 March 2020

1 reference

Studies in mammalian spermatogenesis. II. The spermatogenesis of man

31 March 2020

1 reference

THE CHROMOSOME NUMBER OF MAN

31 March 2020

1 reference

Three chromosome numbers in whites and Japanese

31 March 2020

1 reference

The somatic chromosomes in mongolism

31 March 2020

1 reference

Chromosome translocation as a cause of familial mongolism

31 March 2020

1 reference

21-trisomy/normal mosaicism in an intelligent child with some mongoloid characters

31 March 2020

1 reference

Identification of human chromosomes by DNA-binding fluorescent agents

31 March 2020

1 reference

Distinction between extra G-like chromosomes by quinacrine mustard fluorescence analysis

31 March 2020

1 reference

31 March 2020

1 reference

Molecular mapping of twenty-four features of Down syndrome on chromosome 21.

31 March 2020

1 reference

Down syndrome phenotypes: the consequences of chromosomal imbalance

31 March 2020

1 reference

Down syndrome—a disruption of homeostasis

31 March 2020

1 reference

The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

31 March 2020

1 reference

Clinical and molecular studies in full trisomy 22: further delineation of the phenotype and review of the literature

31 March 2020

1 reference

Report of the committee on the genetic constitution of chromosome 21.

31 March 2020

1 reference

Molecular analysis and breakpoint definition of a set of human chromosome 21 somatic cell hybrids

31 March 2020

1 reference

YAC analysis and minimal tiling path construction for chromosome 21q.

31 March 2020

1 reference

New method for mapping genes in human chromosomes

31 March 2020

1 reference

Radiation hybrid mapping: a somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes

31 March 2020

1 reference

Fractionation of large mammalian DNA restriction fragments using vertical pulsed-field gradient gel electrophoresis

31 March 2020

1 reference

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors

31 March 2020

1 reference

Long-distance restriction mapping of the proximal long arm of human chromosome 21 with Not I linking clones

31 March 2020

1 reference

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

31 March 2020

1 reference

A contiguous Not I restriction map of band q22.3 of human chromosome 21

31 March 2020

1 reference

Preparation and screening of an arrayed human genomic library generated with the P1 cloning system

31 March 2020

1 reference

A high-fidelity physical map of human chromosome 21q in yeast artificial chromosomes

31 March 2020

1 reference

Transcriptome analysis of human autosomal trisomy

31 March 2020

1 reference

Localization and quantitation of human superoxide dismutase using computerized 2-D gel electrophoresis

31 March 2020

1 reference

Somatic Cell Genetic Approaches to Down's Syndrome

31 March 2020

1 reference

Protein variations associated with Down's syndrome, chromosome 21, and Alzheimer's disease.

31 March 2020

1 reference

Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture

31 March 2020

1 reference

Difference gel electrophoresis: a single gel method for detecting changes in protein extracts

31 March 2020

1 reference

Autosomal trisomy in a chimpanzee: resemblance to Down's syndrome

31 March 2020

1 reference

Trisomy in the fetal backcross progeny of male and female metacentric heterozygotes of the mouse. i

31 March 2020

1 reference

Assignment of the gene for cytoplasmic superoxide dismutase ( Sod-1 ) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse

31 March 2020

1 reference

Chromosome 21 of man, 22 of the great apes and 16 of the mouse

31 March 2020

1 reference

Trisomy 16 in the mouse fetus associated with generalized edema and cardiovascular and urinary tract anomalies.

31 March 2020

1 reference

31 March 2020

1 reference

App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome

31 March 2020

1 reference

Gait dynamics in trisomic mice: quantitative neurological traits of Down syndrome

31 March 2020

1 reference

Experimental parameters affecting the Morris water maze performance of a mouse model of Down syndrome.

31 March 2020

1 reference

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome

31 March 2020

1 reference

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

31 March 2020

1 reference

Down's syndrome: morphological remodelling and increased complexity in the neuromuscular junction of transgenic CuZn-superoxide dismutase mice

31 March 2020

1 reference

Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction.

31 March 2020

1 reference

Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome

31 March 2020

1 reference

Harm avoidance, anxiety, and response to novelty in the adolescent S-100beta transgenic mouse: role of serotonin and relevance to Down syndrome

31 March 2020

1 reference

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

31 March 2020

1 reference

Building protein interaction maps for Down's syndrome

31 March 2020

1 reference

Scientific dishonesty: European reflections

31 March 2020

1 reference

A look at a Hispanic and African American population in an urban prenatal diagnostic center: referral reasons, amniocentesis acceptance, and abnormalities detected

31 March 2020

1 reference

An association between low maternal serum α-fetoprotein and fetal chromosomal abnormalities

31 March 2020

1 reference

Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy

31 March 2020

1 reference

Detection of fetal cells with 47,XY,+21 karyotype in maternal peripheral blood

31 March 2020

1 reference

Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome

31 March 2020

1 reference

Maternal metabolic phenotype and risk of Down syndrome: beyond genetics

31 March 2020

1 reference