(Q36011828)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Cellular mechanisms of insulin resistance, lipodystrophy and atherosclerosis induced by HIV protease inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

1 reference

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Rudich A

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Ben-Romano R

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Bashan N

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

Acta Physiologica Scandinavica

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

75-88

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

Lipodystrophy in human immunodeficiency virus patients impairs insulin action and induces defects in beta-cell function

7 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Impaired non-esterified fatty acid suppression is associated with endothelial dysfunction in insulin resistant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

An open-label, prospective, observational study of the incidence of coronary artery disease in patients with hiv infection receiving highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Agent and cell-type specificity in the induction of insulin resistance by HIV protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Effects of free fatty acids (FFA) on glucose metabolism: significance for insulin resistance and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Vascular smooth muscle cell apoptosis in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection

21 January 2018

1 reference

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Ten years of protein kinase B signalling: a hard Akt to follow

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Regulated transport of the glucose transporter GLUT4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Glitazones in lipodystrophy syndrome induced by highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV protease inhibitor-related lipodystrophy syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Images in clinical medicine. Lipodystrophy associated with an HIV-protease inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

No effect of rosiglitazone for treatment of HIV-1 lipoatrophy: randomised, double-blind, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

21 January 2018

HIV-protease inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Combination antiretroviral therapy and the risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Acquired and inherited lipodystrophies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Improved insulin sensitivity and body fat distribution in HIV-infected patients treated with rosiglitazone: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Anti-apoptotic effect of HIV protease inhibitors via direct inhibition of calpain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Increased rates of lipolysis among human immunodeficiency virus-infected men receiving highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Clinical features of acute coronary syndromes in patients with human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Effects of HIV protease inhibitor therapy on lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Oxidant signaling in vascular cell growth, death, and survival : a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Metabolic complications associated with antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV-associated lipodystrophy: pathogenesis, prognosis, treatment, and controversies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Reactive oxygen species activate glucose transport in L6 myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV protease inhibitors stimulate hepatic triglyceride synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Low plasma level of adiponectin is associated with stavudine treatment and lipodystrophy in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

"Buffalo hump" in men with HIV-1 infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Metabolic abnormalities in the diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Premature lesions of the carotid vessels in HIV-1-infected patients treated with protease inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Reversion of metabolic abnormalities after switching from HIV-1 protease inhibitors to nevirapine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Human obesity and thinness, hyperlipidemia, hyperglycemia, and insulin resistance associated with HIV1 protease inhibitors. Prevention by alternating several antiproteases in short sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Adiponectin and leptin levels in HIV-infected subjects with insulin resistance and body fat redistribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Endothelial function in HIV-infected patients receiving protease inhibitor therapy: does immune competence affect cardiovascular risk?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Metabolic effects of indinavir in healthy HIV-seronegative men

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Increased VLDL-apoB and IDL-apoB production rates in nonlipodystrophic HIV-infected patients on a protease inhibitor-containing regimen: a stable isotope kinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Atherosclerosis in type 2 diabetes mellitus and insulin resistance: mechanistic links and therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Alterations in lipid kinetics in men with HIV-dyslipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Molecular regulation of adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Push/pull mechanisms of GLUT4 traffic in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

How an inhibitor of the HIV-I protease modulates proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Accelerated coronary atherosclerosis and arteriosclerosis in young human-immunodeficiency-virus-positive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV protease as a target for retrovirus vector-mediated gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Lipodystrophy in HIV-1-positive patients is associated with insulin resistance in multiple metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Decrease of HIV-1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine. Ritonavir/3TC/ZDV Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Ritonavir inhibition of calcium-activated neutral proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Adiponectin Ameliorates Dyslipidemia Induced by the Human Immunodeficiency Virus Protease Inhibitor Ritonavir in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Endocrine and metabolic evaluation of human immunodeficiency virus-infected patients with evidence of protease inhibitor-associated lipodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Insulin resistance in HIV protease inhibitor-associated diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Lipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

HIV protease inhibitor ritonavir induces cytotoxicity of human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

Protease inhibitors and cardiovascular outcomes in patients with HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-201X.2004.01383.X

10.1111/J.1365-201X.2004.01383.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15654921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference