(Q36015867)

11 August 2017

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title

The role of models in understanding CD8+ T-cell memory (English)

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11 August 2017

1

Rustom Antia

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11 August 2017

3

Rafi Ahmed

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11 August 2017

Vitaly V Ganusov

2

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11 August 2017

1 February 2005

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Nature Reviews Immunology

11 August 2017

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11 August 2017

5

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11 August 2017

101-111

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11 August 2017

2

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The Florey Lecture, 1983: Biological Control, as Exemplified by Smallpox Eradication and Myxomatosis

11 August 2017

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Two hundred years of vaccination.

21 January 2018

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A brief history of the prevention of infectious diseases by immunisations

21 January 2018

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Present status of human HIV vaccine development

21 January 2018

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A new boost for malaria vaccines

21 January 2018

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Progress on new vaccine strategies against chronic viral infections

21 January 2018

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Mathematical and computational challenges in population biology and ecosystems science

21 January 2018

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Uses and abuses of mathematics in biology

21 January 2018

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Immunological memory and protective immunity: understanding their relation

21 January 2018

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Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

21 January 2018

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Estimating the precursor frequency of naive antigen-specific CD8 T cells

21 January 2018

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Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus

21 January 2018

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Different Dynamics of CD4+ and CD8+ T Cell Responses During and After Acute Lymphocytic Choriomeningitis Virus Infection

21 January 2018

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Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.

21 January 2018

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Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy

21 January 2018

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Quantification of cell turnover kinetics using 5-bromo-2'-deoxyuridine.

21 January 2018

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Lymphocyte kinetics: the interpretation of labelling data

21 January 2018

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The rescaling method for quantifying the turnover of cell populations

21 January 2018

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Determination of lymphocyte division by flow cytometry

21 January 2018

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A cellular calculus for signal integration by T cells

21 January 2018

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21 January 2018

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Linear differentiation of cytotoxic effectors into memory T lymphocytes

21 January 2018

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Modelling T-cell memory by genetic marking of memory T cells in vivo

21 January 2018

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The role of antigen-independent persistence of memory cytotoxic T lymphocytes

21 January 2018

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Early programming of T cell populations responding to bacterial infection

21 January 2018

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Cutting edge: antigen-independent CD8 T cell proliferation.

21 January 2018

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Models of CD8+ responses: 1. What is the antigen-independent proliferation program.

21 January 2018

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Comparing antigen-independent mechanisms of T cell regulation.

21 January 2018

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Modelling the impact of antigen kinetics on T-cell activation and response

21 January 2018

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An innate sense of danger

21 January 2018

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Immune evasion strategies of the primate lentiviruses

21 January 2018

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Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 January 2018

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Immunological memory in humans

21 January 2018

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Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

21 January 2018

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Duration of antiviral immunity after smallpox vaccination

21 January 2018

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Cutting Edge: Long-Term B Cell Memory in Humans after Smallpox Vaccination

21 January 2018

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Distinct time effects of vaccination on long-term proliferative and IFN-gamma-producing T cell memory to smallpox in humans

21 January 2018

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Turnover of naive- and memory-phenotype T cells

21 January 2018

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Induction of bystander T cell proliferation by viruses and type I interferon in vivo

21 January 2018

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Turnover of memory-phenotype CD8+ T cells

21 January 2018

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Persistence of memory CD8 T cells in MHC class I-deficient mice

21 January 2018

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In vivo estimates of division and death rates of human T lymphocytes

21 January 2018

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A role for antigen in the maintenance of immunological memory

21 January 2018

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On differences between immunity and immunological memory

21 January 2018

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B-cell memory is short-lived in the absence of antigen.

21 January 2018

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T cell memory is short-lived in the absence of antigen

21 January 2018

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Cytotoxic T-cell memory without antigen

21 January 2018

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Virus-specific CD8+ T-cell memory determined by clonal burst size

21 January 2018

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The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen

21 January 2018

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Class II-independent generation of CD4 memory T cells from effectors.

21 January 2018

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21 January 2018

Tickling memory T cells.

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Is T-cell memory maintained by crossreactive stimulation?

21 January 2018

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Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses.

21 January 2018

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Lymphocyte lifespans: homeostasis, selection and competition

21 January 2018

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Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

21 January 2018

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Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

21 January 2018

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Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

21 January 2018

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A model of human immunodeficiency virus infection in T helper cell clones

21 January 2018

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21 January 2018

Modelling T cell memory.

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Models of immune memory: on the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory

21 January 2018

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Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses

21 January 2018

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Memory CD8 T-cell differentiation during viral infection

21 January 2018

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Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections.

21 January 2018

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Human naive and memory T lymphocytes differ in telomeric length and replicative potential

21 January 2018

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Will telomere erosion lead to a loss of T-cell memory?

21 January 2018

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Fratricide: a mechanism for T memory-cell homeostasis

21 January 2018

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CD8 memory T cells: cross-reactivity and heterologous immunity.

21 January 2018

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Early HIV infection in vivo: branching-process model for studying timing of immune responses and drug therapy.

21 January 2018

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Kinetics of virus-specific CD8+ T cells and the control of human immunodeficiency virus infection

21 January 2018

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Response of naïve and memory CD8+ T cells to antigen stimulation in vivo

21 January 2018

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Cutting edge: rapid in vivo killing by memory CD8 T cells.

21 January 2018

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Cutting edge: rapid in vivo CTL activity by polyoma virus-specific effector and memory CD8+ T cells

21 January 2018

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Modelling viral and immune system dynamics

21 January 2018

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Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation

21 January 2018

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Discrete event modeling of CD4+ memory T cell generation.

21 January 2018

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Independent regulation of lymphocytic choriomeningitis virus-specific T cell memory pools: relative stability of CD4 memory under conditions of CD8 memory T cell loss.

21 January 2018

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

21 January 2018

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Lineage relationship and protective immunity of memory CD8 T cell subsets

21 January 2018

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Exploring the Mechanisms of Primary Antibody Responses to T Cell-Dependent Antigens

21 January 2018

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Somatic hypermutation in B cells: an optimal control treatment.

21 January 2018

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Modeling and optimization of populations subject to time-dependent mutation

21 January 2018

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Memory B-cell persistence is independent of persisting immunizing antigen.

21 January 2018

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Immunological memory to viral infection

21 January 2018

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Humoral immunity due to long-lived plasma cells.

21 January 2018

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Maintenance of serological memory by polyclonal activation of human memory B cells.

21 January 2018

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Concomitant regulation of T-cell activation and homeostasis

21 January 2018

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Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and Survival

21 January 2018

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Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

31 March 2020

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Innate immune recognition and control of adaptive immune responses

31 March 2020

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Virus proteins that counteract host immune defenses

31 March 2020

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The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools

31 March 2020

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CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory

31 March 2020

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T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens

31 March 2020

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T-cell induced pathogenesis in HIV: bystander effects and latent infection

31 March 2020

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Pathology during acute infections: contributions of intracellular pathogens and the CTL response

31 March 2020

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A spatial model of germinal center reactions: cellular adhesion based sorting of B cells results in efficient affinity maturation

31 March 2020

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Some scaling principles for the immune system

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1550

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11 August 2017

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PubMed ID

15662368