(Q36019188)

11 August 2017

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title

Protein-protein interactions in the regulation of the extracellular signal-regulated kinase (English)

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protein-protein interaction

11 August 2017

main subject

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Dana Chuderland

1

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11 August 2017

Rony Seger

series ordinal

2

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11 August 2017

language of work or name

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1 January 2005

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11 August 2017

published in

Molecular Biotechnology

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11 August 2017

volume

29

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11 August 2017

issue

1

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11 August 2017

page(s)

57-74

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https://scigraph.springernature.com/pub.10.1385/mb:29:1:57

11 August 2017

exact match

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cites work

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

12 December 2020

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

1 reference

12 December 2020

Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669

1 reference

12 December 2020

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

1 reference

12 December 2020

Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms

1 reference

12 December 2020

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

1 reference

12 December 2020

A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun

1 reference

12 December 2020

Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins.

1 reference

12 December 2020

Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.

1 reference

12 December 2020

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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12 December 2020

The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site

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12 December 2020

Expression cloning strategies for the identification of adhesion molecules

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12 December 2020

beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis

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12 December 2020

elk-1 proteins interact with MAP kinases

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12 December 2020

The kinase activity of kinase suppressor of Ras1 (KSR1) is independent of bound MEK.

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12 December 2020

Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry

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12 December 2020

IQGAP1 binds ERK2 and modulates its activity

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12 December 2020

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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12 December 2020

Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling.

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12 December 2020

Heterogeneous expression of four MAP kinase isoforms in human tissues

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12 December 2020

Insulin-stimulated expression of c-fos, fra1 and c-jun accompanies the activation of the activator protein-1 (AP-1) transcriptional complex.

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12 December 2020

Yeast go the whole HOG for the hyperosmotic response

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12 December 2020

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

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12 December 2020

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12 December 2020

The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP

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12 December 2020

MEKK1 binds raf-1 and the ERK2 cascade components

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12 December 2020

ERK1 associates with alpha(v)beta 3 integrin and regulates cell spreading on vitronectin

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12 December 2020

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

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12 December 2020

AKAP mediated signal transduction

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12 December 2020

A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway

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12 December 2020

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

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12 December 2020

The MAPK signaling cascade

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12 December 2020

Signal transduction through MAP kinase cascades

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12 December 2020

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

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12 December 2020

ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

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12 December 2020

Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1

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12 December 2020

A conserved docking motif in MAP kinases common to substrates, activators and regulators

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12 December 2020

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

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12 December 2020

Organization and regulation of mitogen-activated protein kinase signaling pathways

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12 December 2020

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

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12 December 2020

A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1.

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12 December 2020

Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK).

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12 December 2020

KSR, a novel protein kinase required for RAS signal transduction

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12 December 2020

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

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12 December 2020

Docking sites on substrate proteins direct extracellular signal-regulated kinase to phosphorylate specific residues

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12 December 2020

The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene.

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12 December 2020

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

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12 December 2020

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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12 December 2020

A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission

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12 December 2020

Extracellular signal-regulated kinase (ERK) interacts with signal transducer and activator of transcription (STAT) 5a

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12 December 2020

Association of mitogen-activated protein kinase with the microtubule cytoskeleton

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12 December 2020

Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies

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12 December 2020

Cutting edge: extracellular signal-regulated kinase activates syk: a new potential feedback regulation of Fc epsilon receptor signaling.

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12 December 2020

On the crawling of animal cells

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12 December 2020

Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes

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12 December 2020

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

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12 December 2020

KSR is a scaffold required for activation of the ERK/MAPK module

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12 December 2020

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

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12 December 2020

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation

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12 December 2020

Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2.

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12 December 2020

Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity

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12 December 2020

ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK

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12 December 2020

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

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12 December 2020

Phosphorylation of MAP Kinases by MAP/ERK Involves Multiple Regions of MAP Kinases

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12 December 2020

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

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12 December 2020

Rsk1 mediates a MEK-MAP kinase cell survival signal

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12 December 2020

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

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12 December 2020

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

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12 December 2020

Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2

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12 December 2020

TFII-I enhances activation of the c-fos promoter through interactions with upstream elements

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12 December 2020

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase

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12 December 2020

Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions

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12 December 2020

Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells

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12 December 2020

ERK2 enters the nucleus by a carrier-independent mechanism

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12 December 2020

Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

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12 December 2020

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

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12 December 2020

Substrate Recognition Domains within Extracellular Signal-regulated Kinase Mediate Binding and Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase-3

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12 December 2020

Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK

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12 December 2020

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

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12 December 2020

Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs

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12 December 2020

Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization

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12 December 2020

KSR: a MAPK scaffold of the Ras pathway?

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12 December 2020

Components of a new human protein kinase signal transduction pathway

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12 December 2020

Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor

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12 December 2020

Molecular interpretation of ERK signal duration by immediate early gene products

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12 December 2020

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

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12 December 2020

Gatekeepers of the nucleus

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12 December 2020

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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12 December 2020

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

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12 December 2020

Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein

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12 December 2020

The ERK cascade as a prototype of MAPK signaling pathways

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12 December 2020

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment

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12 December 2020

Raf-1 activates MAP kinase-kinase

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12 December 2020

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

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12 December 2020

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

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12 December 2020

Dimerization in MAP-kinase signaling

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12 December 2020

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

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12 December 2020

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity

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12 December 2020

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

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12 December 2020

The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

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12 December 2020

Identification of a cytoplasmic-retention sequence in ERK2

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12 December 2020

Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.

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12 December 2020

MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation

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12 December 2020

Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry

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12 December 2020

Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation

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12 December 2020

Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor.

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12 December 2020

Modular structure of a docking surface on MAPK phosphatases

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12 December 2020

A new ERK2 binding protein, Naf1, attenuates the EGF/ERK2 nuclear signaling

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12 December 2020

Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase

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12 December 2020

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

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12 December 2020

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo

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12 December 2020

Extracellular signal-regulated kinase 1c (ERK1c), a novel 42-kilodalton ERK, demonstrates unique modes of regulation, localization, and function

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12 December 2020

The sevenmaker gain-of-function mutation in p42 MAP kinase leads to enhanced signalling and reduced sensitivity to dual specificity phosphatase action

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12 December 2020

Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism

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12 December 2020

beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

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12 December 2020

Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras

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12 December 2020

A Bipartite Mechanism for ERK2 Recognition by Its Cognate Regulators and Substrates

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12 December 2020

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

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12 December 2020

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

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12 December 2020

The stress-activated protein kinase subfamily of c-Jun kinases

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12 December 2020

Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells.

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12 December 2020

Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain

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12 December 2020

Cell-type specific integration of cross-talk between extracellular signal-regulated kinase and cAMP signaling

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12 December 2020

The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor-stimulated rat phaeochromocytoma (PC12) cells

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12 December 2020

Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates

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12 December 2020

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

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12 December 2020

Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function

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12 December 2020

Biochemistry and biology of the inducible multifunctional transcription factor TFII-I.

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12 December 2020

Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module

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12 December 2020

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

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12 December 2020

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12 December 2020

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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12 December 2020

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

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12 December 2020

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.

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12 December 2020

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

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12 December 2020

Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists

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12 December 2020

The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation

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12 December 2020

IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation

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12 December 2020

Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

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12 December 2020

The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions.

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12 December 2020

Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase

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12 December 2020

ERK activation induces phosphorylation of Elk-1 at multiple S/T-P motifs to high stoichiometry

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12 December 2020

Structure and organization of the mouse elk1 gene

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12 December 2020

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

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12 December 2020

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

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12 December 2020

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

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12 December 2020

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

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12 December 2020

Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.

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12 December 2020

The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.

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12 December 2020

cPLA2 is phosphorylated and activated by MAP kinase

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12 December 2020

The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity

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12 December 2020

Mitogen regulation of c-Raf-1 protein kinase activity toward mitogen-activated protein kinase-kinase

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12 December 2020

The death effector domain of PEA-15 is involved in its regulation of integrin activation

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12 December 2020

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

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12 December 2020

Identifiers

DOI

10.1385/MB:29:1:57

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Dimensions Publication ID

11 August 2017

1020650328

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