(Q36019436)

11 August 2017

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title

How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery (English)

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11 August 2017

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Larry H Thompson

1

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11 August 2017

John M Hinz

series ordinal

2

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11 August 2017

N Alice Yamada

series ordinal

3

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11 August 2017

Nigel J Jones

series ordinal

4

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11 August 2017

publication date

1 March 2005

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Environmental and Molecular Mutagenesis

11 August 2017

published in

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11 August 2017

volume

45

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11 August 2017

issue

2-3

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11 August 2017

page(s)

128-142

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Is Fanconi anemia caused by a defect in the processing of DNA damage?

11 August 2017

cites work

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Repair of DNA interstrand cross-links

21 January 2018

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Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

21 January 2018

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Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing

21 January 2018

1 reference

The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents

21 January 2018

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The genetics of FANCC and FANCG in familial pancreatic cancer

21 January 2018

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Recombinational DNA repair and human disease

21 January 2018

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Accelerated telomere shortening in Fanconi anemia fibroblasts--a longitudinal study

21 January 2018

1 reference

7 January 2021

Cancer in Fanconi anemia, 1927-2001

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7 January 2021

ATR couples FANCD2 monoubiquitination to the DNA-damage response

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7 January 2021

Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens

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7 January 2021

RecQ helicases: suppressors of tumorigenesis and premature aging.

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7 January 2021

Genetic basis of Fanconi anemia

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7 January 2021

Xrcc3 is required for assembly of Rad51 complexes in vivo

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7 January 2021

Multiple TPR motifs characterize the Fanconi anemia FANCG protein

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7 January 2021

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

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7 January 2021

The Fanconi anaemia genome stability and tumour suppressor network.

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7 January 2021

siRNA depletion of BRCA1, but not BRCA2, causes increased genome instability in Fanconi anemia cells.

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7 January 2021

Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia

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7 January 2021

Damage-resistant DNA synthesis in Fanconi anemia cells treated with a DNA cross-linking agent

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7 January 2021

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

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7 January 2021

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

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7 January 2021

Multiplicity reactivation and mutagenesis of trimethylpsoralen-damaged herpes virus in normal and Fanconi's anaemia cells

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7 January 2021

Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1

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7 January 2021

Cellular function of the Fanconi anemia pathway

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7 January 2021

The Fanconi anaemia/BRCA pathway

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7 January 2021

Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block

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7 January 2021

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

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7 January 2021

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

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7 January 2021

Attenuation of the formation of DNA-repair foci containing RAD51 in Fanconi anaemia

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7 January 2021

The Fanconi anemia group C gene product: signaling functions in hematopoietic cells.

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7 January 2021

BRCA1 interacts directly with the Fanconi anemia protein FANCA

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7 January 2021

Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability

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7 January 2021

Cross-link repair in human cells and its possible defect in Fanconi's anemia cells

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7 January 2021

Fanconi anemia protein, FANCG, is a phosphoprotein and is upregulated with FANCA after TNF-alpha treatment

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7 January 2021

The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage

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7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

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7 January 2021

The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light

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7 January 2021

Impaired DNA damage-induced nuclear Rad51 foci formation uniquely characterizes Fanconi anemia group D1

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7 January 2021

Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems

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7 January 2021

Fanconi anemia and DNA repair

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7 January 2021

Telomere shortening in Fanconi anaemia demonstrated by a direct FISH approach

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7 January 2021

A model for replication repair in mammalian cells

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7 January 2021

FANCD2 protein is expressed in proliferating cells of human tissues that are cancer‐prone in Fanconi anaemia

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7 January 2021

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

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7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

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7 January 2021

Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways

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7 January 2021

Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1

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7 January 2021

Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

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7 January 2021

Effect of oxygen tension on chromosomal aberrations in Fanconi anaemia

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7 January 2021

The emerging genetic and molecular basis of Fanconi anaemia

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7 January 2021

Overexpressed thioredoxin compensates Fanconi anemia related chromosomal instability

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7 January 2021

Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice

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7 January 2021

Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3.

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7 January 2021

Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia

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7 January 2021

Cloning and characterization of Chinese hamster p53 cDNA.

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7 January 2021

The Fanconi anemia gene product FANCF is a flexible adaptor protein

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7 January 2021

Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes

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7 January 2021

Abnormal telomere metabolism in Fanconi's anaemia correlates with genomic instability and the probability of developing severe aplastic anaemia

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7 January 2021

Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.

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7 January 2021

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

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7 January 2021

Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance.

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7 January 2021

Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links

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7 January 2021

Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway

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7 January 2021

A novel ubiquitin ligase is deficient in Fanconi anemia

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7 January 2021

X-linked inheritance of Fanconi anemia complementation group B

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7 January 2021

A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome

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7 January 2021

The Fanconi anemia core complex associates with chromatin during S phase

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7 January 2021

Rescue of arrested replication forks by homologous recombination

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7 January 2021

Interaction of FANCD2 and NBS1 in the DNA damage response

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7 January 2021

Promoter hypermethylation of FANCF: disruption of Fanconi Anemia-BRCA pathway in cervical cancer

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7 January 2021

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

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7 January 2021

The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair

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7 January 2021

Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.

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7 January 2021

XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding

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7 January 2021

Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex

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7 January 2021

FANCE: the link between Fanconi anaemia complex assembly and activity

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7 January 2021

Fanconi anaemia proteins: major roles in cell protection against oxidative damage

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7 January 2021

The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors

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7 January 2021

FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity

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7 January 2021

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

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7 January 2021

The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality

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7 January 2021

Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus

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7 January 2021

Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins

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7 January 2021

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

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7 January 2021

DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein

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7 January 2021

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways

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7 January 2021

DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein

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7 January 2021

BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks

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7 January 2021

Fanconi anaemia cells are not uniformly deficient in unhooking of DNA interstrand crosslinks, induced by mitomycin C or 8-methoxypsoralen plus UVA.

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7 January 2021

Positive torsional strain causes the formation of a four-way junction at replication forks

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7 January 2021

Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport

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7 January 2021

The Fanconi anemia pathway and the DNA interstrand cross-links repair

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7 January 2021

Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway

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7 January 2021

The role of oxygen metabolism for the pathological phenotype of Fanconi anemia

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7 January 2021

Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway

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7 January 2021

Frequencies of HPRT- lymphocytes and glycophorin A variants erythrocytes in Fanconi anemia patients, their parents and control donors

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7 January 2021

Arrest of S-phase progression is impaired in Fanconi anemia cells

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7 January 2021

A novel diagnostic screen for defects in the Fanconi anemia pathway

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7 January 2021

Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells

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7 January 2021

Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects

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7 January 2021

Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links

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7 January 2021

The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC

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7 January 2021

S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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7 January 2021

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

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7 January 2021

Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors

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7 January 2021

New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant

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7 January 2021

The Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartments

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7 January 2021

Positional cloning of a novel Fanconi anemia gene, FANCD2

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7 January 2021

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7 January 2021

Function and sequence analyses of tumor suppressor gene p53 of CHO.K1 cells

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7 January 2021

BRCA1-independent ubiquitination of FANCD2

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7 January 2021

A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA

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7 January 2021

The interplay of Fanconi anemia proteins in the DNA damage response

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7 January 2021

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

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7 January 2021

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

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7 January 2021

The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange

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7 January 2021

Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia

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7 January 2021

Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells

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7 January 2021

Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination

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7 January 2021

Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9

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7 January 2021

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

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7 January 2021

Hydrogen peroxide: effects on DNA, chromosomes, cell cycle and apoptosis induction in Fanconi's anemia cell lines

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7 January 2021

Identifiers

DOI

10.1002/EM.20109

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11 August 2017

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