(Q36020648)

11 August 2017

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title

Role of the liver in the control of carbohydrate and lipid homeostasis (English)

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11 August 2017

Postic C

1

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11 August 2017

Dentin R

series ordinal

2

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11 August 2017

Girard J

series ordinal

3

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11 August 2017

publication date

1 November 2004

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11 August 2017

published in

Diabetes and Metabolism

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11 August 2017

volume

30

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11 August 2017

issue

5

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11 August 2017

page(s)

398-408

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Pathogenesis of NIDDM. A balanced overview

11 August 2017

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7 January 2021

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Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

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7 January 2021

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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7 January 2021

Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production

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7 January 2021

The direct and indirect effects of insulin on hepatic glucose production in vivo

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7 January 2021

Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats

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7 January 2021

Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.

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7 January 2021

Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice

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7 January 2021

Rat hepatic microsomal glucose-6-phosphatase protein levels are increased in streptozotocin-induced diabetes

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7 January 2021

Glucose regulates in vivo glucose-6-phosphatase gene expression in the liver of diabetic rats.

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7 January 2021

Metabolic Impact of Adenovirus-mediated Overexpression of the Glucose-6-phosphatase Catalytic Subunit in Hepatocytes

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7 January 2021

Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase

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7 January 2021

Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation

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7 January 2021

Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression

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7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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7 January 2021

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

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7 January 2021

Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins

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7 January 2021

A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin

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7 January 2021

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

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7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

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7 January 2021

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

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7 January 2021

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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7 January 2021

Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription

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7 January 2021

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

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7 January 2021

Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo

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7 January 2021

Phosphatidylinositol 3-kinase and protein kinase C contribute to the inhibition by interleukin 6 of phosphoenolpyruvate carboxykinase gene expression in cultured rat hepatocytes

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7 January 2021

Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis

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7 January 2021

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

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7 January 2021

Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes.

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7 January 2021

Cell-specific roles of glucokinase in glucose homeostasis.

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7 January 2021

Gene-altered mice and metabolic flux control

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7 January 2021

Correction of diabetic alterations by glucokinase.

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7 January 2021

Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose Metabolism

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7 January 2021

Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver

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7 January 2021

Cell-specific Expression and Regulation of a Glucokinase Gene Locus Transgene

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7 January 2021

Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes

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7 January 2021

Allosteric activators of glucokinase: potential role in diabetes therapy

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7 January 2021

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators

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7 January 2021

Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects.

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7 January 2021

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7 January 2021

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7 January 2021

Control of glycogen deposition.

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7 January 2021

PPP1R6, a novel member of the family of glycogen-targetting subunits of protein phosphatase 1

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7 January 2021

Purification of the hepatic glycogen-associated form of protein phosphatase-1 by microcystin-Sepharose affinity chromatography

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7 January 2021

PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism

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7 January 2021

PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance

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7 January 2021

Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen

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7 January 2021

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

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7 January 2021

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

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7 January 2021

Glucose regulation of gene transcription

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7 January 2021

Regulation of the expression of lipogenic enzyme genes by carbohydrate

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7 January 2021

Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity

1 reference

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7 January 2021

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970133-7

7 January 2021

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

1 reference

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7 January 2021

Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter

1 reference

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7 January 2021

Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.

1 reference

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7 January 2021

Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver.

1 reference

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7 January 2021

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

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7 January 2021

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

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7 January 2021

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

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7 January 2021

Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver

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7 January 2021

SREBPs suppress IRS-2-mediated insulin signalling in the liver

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7 January 2021

Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.

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7 January 2021

Rat glucokinase gene: structure and regulation by insulin

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7 January 2021

Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription

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7 January 2021

Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes

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https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970133-7

7 January 2021

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

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7 January 2021

Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970133-7

7 January 2021

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970133-7

7 January 2021

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970133-7

7 January 2021

10.1016/S1262-3636(07)70133-7

Identifiers

DOI

1 reference

11 August 2017

1 reference