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Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?
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scholarly article
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stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
review article
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stated in
Europe PubMed Central
title
Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
author name string
D Grahame Hardie
series ordinal
1
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Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
language of work or name
English
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publication date
7 July 2015
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Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
number of pages
5
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inferred from page(s)
published in
Clinical Cancer Research
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stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
volume
21
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Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
page(s)
3836-3840
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stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
issue
17
1 reference
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Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
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MicroRNA-301a modulates doxorubicin resistance in osteosarcoma cells by targeting AMP-activated protein kinase alpha 1.
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AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells.
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Structure of mammalian AMPK and its regulation by ADP
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Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
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Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
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2 October 2017
AMPK phosphorylation of raptor mediates a metabolic checkpoint
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2 October 2017
Structural basis for AMP binding to mammalian AMP-activated protein kinase
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2 October 2017
LKB1 modulates lung cancer differentiation and metastasis
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2 October 2017
Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta
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2 October 2017
5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
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2 October 2017
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
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2 October 2017
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
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2 October 2017
Metformin and reduced risk of cancer in diabetic patients
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Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.
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2 October 2017
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
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2 October 2017
CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations
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2 October 2017
TSC2 mediates cellular energy response to control cell growth and survival
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2 October 2017
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
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2 October 2017
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
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2 October 2017
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
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2 October 2017
AMP-activated protein kinase: the energy charge hypothesis revisited
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2 October 2017
Role of AMP-activated protein kinase in mechanism of metformin action
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2 October 2017
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line
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2 October 2017
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
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2 October 2017
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
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2 October 2017
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
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2 October 2017
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
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2 October 2017
Degradation of AMPK by a cancer-specific ubiquitin ligase
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PubMed Central
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11 July 2018
AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis
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11 July 2018
AMPK is a direct adenylate charge-regulated protein kinase.
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23 September 2018
Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo.
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23 September 2018
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
1 reference
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23 September 2018
The Snf1 protein kinase controls the induction of genes of the iron uptake pathway at the diauxic shift in Saccharomyces cerevisiae
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23 September 2018
Identifiers
DOI
10.1158/1078-0432.CCR-14-3300
1 reference
stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
PMCID
4558946
1 reference
stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
PubMed ID
26152739
1 reference
stated in
Europe PubMed Central
PMCID
4558946
retrieved
11 August 2017
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