(Q39372073)

11 September 2017

title

Deregulated MYC expression induces dependence upon AMPK-related kinase 5. (English)

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11 September 2017

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13

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11 September 2017

12

Lars Zender

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Daniel J Murphy

object named as

Daniel J Murphy

14

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author name string

Lidan Liu

1

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11 September 2017

Jannes Ulbrich

2

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11 September 2017

Judith Müller

3

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11 September 2017

Torsten Wüstefeld

4

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11 September 2017

Lukas Aeberhard

5

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11 September 2017

Theresia R Kress

6

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11 September 2017

Nathiya Muthalagu

7

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11 September 2017

Lukas Rycak

8

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11 September 2017

Ramona Rudalska

9

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11 September 2017

Roland Moll

10

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11 September 2017

Stefan Kempa

11

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11 September 2017

Lars Zender

12

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11 September 2017

language of work or name

English

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publication date

28 March 2012

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11 September 2017

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11 September 2017

volume

483

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11 September 2017

issue

7391

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11 September 2017

page(s)

608-612

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describes a project that uses

11 September 2017

HCC4977

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cites work

MYC-induced cancer cell energy metabolism and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

ARK5 is a tumor invasion-associated factor downstream of Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Regulation of ploidy and senescence by the AMPK-related kinase NUAK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE10927

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Cdk2 suppresses cellular senescence induced by the c-myc oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

A plastid-localized glycogen synthase kinase 3 modulates stress tolerance and carbohydrate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

An automated GCxGC-TOF-MS protocol for batch-wise extraction and alignment of mass isotopomer matrixes from differential 13C-labelling experiments: a case study for photoautotrophic-mixotrophic grown Chlamydomonas reinhardtii cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Andromeda: a peptide search engine integrated into the MaxQuant environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10927

21 January 2018

Identifiers

DOI

10.1038/NATURE10927

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Dimensions Publication ID

11 September 2017

1014818407

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